Tizoxanide
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MedKoo CAT#: 317144

CAS#: 173903-47-4

Description: Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. Tizoxanide is a potent inhibitor of hepatitis B virus and hepatitis C virus replication.


Chemical Structure

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Tizoxanide
CAS# 173903-47-4

Theoretical Analysis

MedKoo Cat#: 317144
Name: Tizoxanide
CAS#: 173903-47-4
Chemical Formula: C10H7N3O4S
Exact Mass: 265.01573
Molecular Weight: 265.24
Elemental Analysis: C, 45.28; H, 2.66; N, 15.84; O, 24.13; S, 12.09

Price and Availability

Size Price Availability Quantity
50.0mg USD 450.0 2 Weeks
100.0mg USD 650.0 2 Weeks
200.0mg USD 950.0 2 Weeks
500.0mg USD 1950.0 2 Weeks
1.0g USD 2950.0 2 Weeks
2.0g USD 4650.0 2 Weeks
5.0g USD 6950.0 2 Weeks
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Synonym: NSC-697856; NSC697856; NSC697856; Tizoxanide; Desacetylnitazoxanide; Desacetyl-nitazoxanide.

IUPAC/Chemical Name: 2-hydroxy-N-(5-nitrothiazol-2-yl)benzamide

InChi Key: FDTZUTSGGSRHQF-UHFFFAOYSA-N

InChi Code: InChI=1S/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15)

SMILES Code: O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=CC=C2O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 265.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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