WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 317144
CAS#: 173903-47-4
Description: Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. Tizoxanide is a potent inhibitor of hepatitis B virus and hepatitis C virus replication.
MedKoo Cat#: 317144
Name: Tizoxanide
CAS#: 173903-47-4
Chemical Formula: C10H7N3O4S
Exact Mass: 265.01573
Molecular Weight: 265.24
Elemental Analysis: C, 45.28; H, 2.66; N, 15.84; O, 24.13; S, 12.09
Synonym: NSC-697856; NSC697856; NSC697856; Tizoxanide; Desacetylnitazoxanide; Desacetyl-nitazoxanide.
IUPAC/Chemical Name: 2-hydroxy-N-(5-nitrothiazol-2-yl)benzamide
InChi Key: FDTZUTSGGSRHQF-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15)
SMILES Code: O=C(NC1=NC=C([N+]([O-])=O)S1)C2=CC=CC=C2O
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 265.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
