WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 522454
CAS#: 1623101-11-0
Description: VU0483605 is a potent and selective positive allosteric modulator (PAM) of mGluR1, displaying EC50 values of 0.39 and 0.36 μM at human and rat receptors, respectively, and no activity as a mGlu4 PAM (EC50 >10 μM).
MedKoo Cat#: 522454
Name: VU0483605
CAS#: 1623101-11-0
Chemical Formula: C20H10Cl3N3O3
Exact Mass: 444.97877
Molecular Weight: 446.67
Elemental Analysis: C, 53.78; H, 2.26; Cl, 23.81; N, 9.41; O, 10.75
VU0483605, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.
Synonym: VU0483605, VU-0483605, VU 048360
IUPAC/Chemical Name: 3-chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide
InChi Key: HJQXPBKPTGWZCF-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H10Cl3N3O3/c21-12-4-1-3-11-16(12)20(29)26(19(11)28)15-7-6-10(9-14(15)23)25-18(27)17-13(22)5-2-8-24-17/h1-9H,(H,25,27)
SMILES Code: O=C(C1=NC=CC=C1Cl)NC2=CC=C(N(C(C3=C4C=CC=C3Cl)=O)C4=O)C(Cl)=C2
The following data is based on the product molecular weight 446.67 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
