CDy9

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MedKoo CAT#: 522446

CAS#: 1800205-57-5

Description: CDy9 is a highly selective fluorescent probe for the detection and isolation of mESC using fluorescence microscopy and flow cytometry. CDy9 allows the detection and isolation of intact stem cells with marginal impact on their function and capabilities. CDy9 may be a non-invasive biotechnological tool for the preparation, purification and characterization of mESC. Stem cell research has gathered immense attention in the past decade due to the remarkable ability of stem cells for self-renewal and tissue-specific differentiation. Despite having numerous advancements in stem cell isolation and manipulation techniques, there is a need for highly reliable probes for the specific detection of live stem cells.


Chemical Structure

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CDy9
CAS# 1800205-57-5

Theoretical Analysis

MedKoo Cat#: 522446
Name: CDy9
CAS#: 1800205-57-5
Chemical Formula: C23H23BClF2N3O2
Exact Mass: 457.15399
Molecular Weight: 457.71
Elemental Analysis: C, 60.36; H, 5.07; B, 2.36; Cl, 7.75; F, 8.30; N, 9.18; O, 6.99

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Synonym: CDy9; CDy-9; CDy 9.

IUPAC/Chemical Name: (E)-2-chloro-N-(2-(5,5-difluoro-3-(2-hydroxy-5-methylstyryl)-1-methyl-5H-4l4,5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)ethyl)acetamide

InChi Key: ZSQGDQRUQOAGGB-VOTSOKGWSA-N

InChi Code: InChI=1S/C23H23BClF2N3O2/c1-15-5-8-21(31)17(12-15)6-7-18-13-16(2)23-19(9-10-28-22(32)14-25)20-4-3-11-29(20)24(26,27)30(18)23/h3-8,11-13,31H,9-10,14H2,1-2H3,(H,28,32)/b7-6+

SMILES Code: CC1=CC(/C=C/C2=CC(C)=CC=C2O)=[N+]3C1=C(CCNC(CCl)=O)C4=CC=CN4[B-]3(F)F

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 457.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Chandran Y, Kang NY, Park SJ, Husen Alamudi S, Kim JY, Sahu S, Su D, Lee J,
Vendrell M, Chang YT. A highly selective fluorescent probe for direct detection
and isolation of mouse embryonic stem cells. Bioorg Med Chem Lett. 2015 Nov
1;25(21):4862-5. doi: 10.1016/j.bmcl.2015.06.037. Epub 2015 Jun 16. PubMed PMID:
26115574.

CDy9

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