WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 522446
Description: CDy9 is a highly selective fluorescent probe for the detection and isolation of mESC using fluorescence microscopy and flow cytometry. CDy9 allows the detection and isolation of intact stem cells with marginal impact on their function and capabilities. CDy9 may be a non-invasive biotechnological tool for the preparation, purification and characterization of mESC. Stem cell research has gathered immense attention in the past decade due to the remarkable ability of stem cells for self-renewal and tissue-specific differentiation. Despite having numerous advancements in stem cell isolation and manipulation techniques, there is a need for highly reliable probes for the specific detection of live stem cells.
MedKoo Cat#: 522446
Chemical Formula: C23H23BClF2N3O2
Exact Mass: 457.15399
Molecular Weight: 457.71
Elemental Analysis: C, 60.36; H, 5.07; B, 2.36; Cl, 7.75; F, 8.30; N, 9.18; O, 6.99
Synonym: CDy9; CDy-9; CDy 9.
IUPAC/Chemical Name: (E)-2-chloro-N-(2-(5,5-difluoro-3-(2-hydroxy-5-methylstyryl)-1-methyl-5H-4l4,5l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)ethyl)acetamide
InChi Key: ZSQGDQRUQOAGGB-VOTSOKGWSA-N
InChi Code: InChI=1S/C23H23BClF2N3O2/c1-15-5-8-21(31)17(12-15)6-7-18-13-16(2)23-19(9-10-28-22(32)14-25)20-4-3-11-29(20)24(26,27)30(18)23/h3-8,11-13,31H,9-10,14H2,1-2H3,(H,28,32)/b7-6+
SMILES Code: CC1=CC(/C=C/C2=CC(C)=CC=C2O)=[N+]3C1=C(CCNC(CCl)=O)C4=CC=CN4[B-]3(F)F
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 457.71 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Chandran Y, Kang NY, Park SJ, Husen Alamudi S, Kim JY, Sahu S, Su D, Lee J,
Vendrell M, Chang YT. A highly selective fluorescent probe for direct detection
and isolation of mouse embryonic stem cells. Bioorg Med Chem Lett. 2015 Nov
1;25(21):4862-5. doi: 10.1016/j.bmcl.2015.06.037. Epub 2015 Jun 16. PubMed PMID: