WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 610230
Description: 4-(Trifluoromethyl)phenylboronic acid undergoes direct cross-coupling with allyl alcohols. One use of this drug is to N-arylate imidazoles and amines with copper-exchanged fluorapatite, as well as used in microwave-promoted cross-coupling with acid chlorides leading to aryl ketones. It contains varying amounts of anhydride.
MedKoo Cat#: 610230
Name: 4-(Trifluoromethyl)phenylboronic acid
Chemical Formula: C7H6BF3O2
Exact Mass: 190.04129
Molecular Weight: 189.93
Elemental Analysis: C, 44.27; H, 3.18; B, 5.69; F, 30.01; O, 16.85
4-(Trifluoromethyl)phenylboronic acid, purity > 98%, is in stock. Current shipping out time is about 10 days after order is received.
Synonym: α,α,α-Trifluoro-p-tolylboronic acid, 4-(Trifluoromethyl)benzeneboronic acid, [p-(Trifluoromethyl)phenyl]boronic acid
IUPAC/Chemical Name: [4-(trifluoromethyl)phenyl]boronic acid
InChi Key: ALMFIOZYDASRRC-UHFFFAOYSA-N
InChi Code: InChI=1S/C7H6BF3O2/c9-7(10,11)5-1-3-6(4-2-5)8(12)13/h1-4,12-13H
SMILES Code: B(C1=CC=C(C=C1)C(F)(F)F)(O)O
The following data is based on the product molecular weight 189.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
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5: Jordan F, Polgar L, Tous G. Proton magnetic resonance studies of the states of ionization of histidines in native and modified subtilisins. Biochemistry. 1985 Dec 17;24(26):7711-7. PubMed PMID: 3912007.
6: Poole CF, Johansson L, Vessman J. Formation of electron-capturing derivatives of alprenolol by transboronation: application to the determination of alprenolol in plasma. J Chromatogr. 1980 Jun 27;194(3):365-77. PubMed PMID: 7391216.