WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 522418
Description: Intepirdine, also known as SB-742457 and RVT-101, is a selective 5-HT6 receptor antagonist with potential cognition, memory, and learning-enhancing effects. It was under development by GlaxoSmithKline for the treatment of Alzheimer's disease and demonstrated some preliminary efficacy in phase II clinical trials. SB742457 can reverse age-related declines in delayed non-match-to-sample performance (DNMS). SB742457 shows increasing pro-cognitive effects in patients with AD.
MedKoo Cat#: 522418
Chemical Formula: C19H19N3O2S
Exact Mass: 353.1198
Molecular Weight: 353.44
Elemental Analysis: C, 64.57; H, 5.42; N, 11.89; O, 9.05; S, 9.07
Intepirdine (SB742457), purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.
Synonym: SB742457; SB 742457; SB-742457; RVT-101; RVT 101; RVT101. intepirdine.
IUPAC/Chemical Name: 3-Phenylsulfonyl-8-(piperazin-1-yl)quinoline
InChi Key: JJZFWROHYSMCMU-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H19N3O2S/c23-25(24,16-6-2-1-3-7-16)17-13-15-5-4-8-18(19(15)21-14-17)22-11-9-20-10-12-22/h1-8,13-14,20H,9-12H2
SMILES Code: O=S(C1=CC2=CC=CC(N3CCNCC3)=C2N=C1)(C4=CC=CC=C4)=O
The following data is based on the product molecular weight 353.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|