WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 407158

CAS#: 926259-99-6

Description: BG45 is a potent and selective HDAC3 inhibitor inhibitor with selectivity for HDAC3 (IC50 = 289 nM) over HDAC1, 2. BG45 did not inihibit HDAC6. BG45 signigicantly inhibited tumor growth in a mouse model of multiple myeloma either alone and synergistically in combination with bortezomib. HDAC3 represents a promising therapeutic target, and validate a prototype novel HDAC3 inhibitor BG45 in MM.

Chemical Structure

CAS# 926259-99-6

Theoretical Analysis

MedKoo Cat#: 407158
Name: BG45
CAS#: 926259-99-6
Chemical Formula: C11H10N4O
Exact Mass: 214.08546
Molecular Weight: 214.23
Elemental Analysis: C, 61.67; H, 4.71; N, 26.15; O, 7.47

Size Price Shipping out time Quantity
10mg USD 110 Same day
25mg USD 150 Same day
50mg USD 250 Same day
100mg USD 450 Same day
200mg USD 750 Same day
500mg USD 1250 Same day
1g USD 1950 Same day
2g USD 2950 Same day
Inquire bulk and customized quantity

Pricing updated 2021-03-09. Prices are subject to change without notice.

BG45, purity > 98%, is in stock. The same day shipping after order is received.

Synonym: BG45; BG-45; BG 45.

IUPAC/Chemical Name: N-(2-Aminophenyl)pyrazine-2-carboxamide


InChi Code: InChI=1S/C11H10N4O/c12-8-3-1-2-4-9(8)15-11(16)10-7-13-5-6-14-10/h1-7H,12H2,(H,15,16)


Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Preparing Stock Solutions

The following data is based on the product molecular weight 214.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Minami J, Suzuki R, Mazitschek R, Gorgun G, Ghosh B, Cirstea D, Hu Y, Mimura
N, Ohguchi H, Cottini F, Jakubikova J, Munshi NC, Haggarty SJ, Richardson PG,
Hideshima T, Anderson KC. Histone deacetylase 3 as a novel therapeutic target in
multiple myeloma. Leukemia. 2014 Mar;28(3):680-9. doi: 10.1038/leu.2013.231. Epub
2013 Aug 5. PubMed PMID: 23913134; PubMed Central PMCID: PMC4165599.