WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 407152

CAS#: 1613028-81-1

Description: SR9243 is a potent and selective LXR inverse agonist. SR9243 kills cancer cells by inhibiting lipid production and the Warburg effect. SR9243 induces cell death in multiple types of cancer and does not cause the side effects that have derailed previous attempts to target these processes. In cancer cells, SR9243 significantly inhibited the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression. SR9243 induced apoptosis in tumors without inducing weight loss, hepatotoxicity, or inflammation. Malignant cells exhibit aerobic glycolysis (the Warburg effect) and become dependent on de novo lipogenesis, which sustains rapid proliferation and resistance to cellular stress.

Chemical Structure

CAS# 1613028-81-1

Theoretical Analysis

MedKoo Cat#: 407152
Name: SR9243
CAS#: 1613028-81-1
Chemical Formula: C31H32BrNO4S2
Exact Mass: 625.09561
Molecular Weight: 626.62
Elemental Analysis: C, 59.42; H, 5.15; Br, 12.75; N, 2.24; O, 10.21; S, 10.23

Size Price Shipping out time Quantity
10mg USD 90 Same day
25mg USD 150 Same day
50mg USD 250 Same day
100mg USD 450 Same day
200mg USD 750 Same day
500mg USD 1250 Same day
1g USD 1950 2 Weeks
2g USD 3650 2 Weeks
5g USD 5650 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-03-02. Prices are subject to change without notice.

SR9243, purity > 98%, is in stock. The same day shipping after order is received.

Synonym: SR9243; SR-9243; SR 9243.

IUPAC/Chemical Name: N-(3-bromophenethyl)-2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide

InChi Key: InChI=1S/C31H32BrNO4S2/c1-22-17-23(2)31(24(3)18-22)39(36,37)33(16-15-25-7-5-9-29(32)19-25)21-26-11-13-27(14-12-26)28-8-6-10-30(20-28)38(4,34)35/h5-14,17-20H,15-16,21H2,1-4H3


SMILES Code: O=S(C1=C(C)C=C(C)C=C1C)(N(CCC2=CC=CC(Br)=C2)CC3=CC=C(C4=CC=CC(S(=O)(C)=O)=C4)C=C3)=O

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Preparing Stock Solutions

The following data is based on the product molecular weight 626.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: New Compound Targets Warburg Effect. Cancer Discov. 2015 Sep;5(9):898. doi:
10.1158/2159-8290.CD-NB2015-108. Epub 2015 Jul 24. PubMed PMID: 26209538.

2: Flaveny CA, Griffett K, El-Gendy Bel-D, Kazantzis M, Sengupta M, Amelio AL,
Chatterjee A, Walker J, Solt LA, Kamenecka TM, Burris TP. Broad Anti-tumor
Activity of a Small Molecule that Selectively Targets the Warburg Effect and
Lipogenesis. Cancer Cell. 2015 Jul 13;28(1):42-56. doi:
10.1016/j.ccell.2015.05.007. Epub 2015 Jun 25. PubMed PMID: 26120082.