WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 317114
CAS#: 53179-13-8
Description: Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.
MedKoo Cat#: 317114
Name: Pirfenidone
CAS#: 53179-13-8
Chemical Formula: C12H11NO
Exact Mass: 185.08406
Molecular Weight: 185.22
Elemental Analysis: C, 77.81; H, 5.99; N, 7.56; O, 8.64
Pirfenidone, purity > 98%, is in stock. The same day shipping after order received.
Synonym: AMR69; AMR-69; AMR 69; Pirfenidone; brand name: Pirespa; Pirfenex; Deskar, Esbriet; Etuary.
IUPAC/Chemical Name: 5-methyl-1-phenyl-2-(1H)-pyridone
InChi Key: ISWRGOKTTBVCFA-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3
SMILES Code: O=C1C=CC(C)=CN1C2=CC=CC=C2
The following data is based on the product molecular weight 185.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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