WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 600137
CAS#: 574-84-5
Description: Fraxetin is an O-methylated coumarin found in Fraxinus rhynchophylla. Fraxin is a glucoside of fraxetin.
MedKoo Cat#: 600137
Name: Fraxetin
CAS#: 574-84-5
Chemical Formula: C10H8O5
Exact Mass: 208.03717
Molecular Weight: 208.17
Elemental Analysis: C, 57.70; H, 3.87; O, 38.43
Synonym: Fraxetin
IUPAC/Chemical Name: 7,8-dihydroxy-6-methoxychromen-2-one
InChi Key: HAVWRBANWNTOJX-UHFFFAOYSA-N
InChi Code: InChI=1S/C10H8O5/c1-14-6-4-5-2-3-7(11)15-10(5)9(13)8(6)12/h2-4,12-13H,1H3
SMILES Code: O=C1C=CC2=C(O1)C(O)=C(O)C(OC)=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO.
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 208.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Xia YL, Liang SC, Zhu LL, Ge GB, He GY, Ning J, Lv X, Ma XC, Yang L, Yang SL. Identification and characterization of human UDP-glucuronosyltransferases responsible for the glucuronidation of fraxetin. Drug Metab Pharmacokinet. 2014;29(2):135-40. Epub 2013 Sep 10. PubMed PMID: 24025985.
