Epicatechin gallate
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MedKoo CAT#: 600132

CAS#: 1257-08-5

Description: Epicatechin gallate (ECG) is a flavan-3-ol, a type of flavonoid, present in green tea. It is also reported in buckwheat and in grape. The tea component epicatechin gallate is being researched because in vitro experiments showed it can reverse methicillin resistance in bacteria like Staphylococcus aureus. If confirmed, this means the combined intake of a tea extract containing this component might also enhance the effectiveness of methicillin treatment against some resistant bacteria in vivo.


Chemical Structure

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Epicatechin gallate
CAS# 1257-08-5

Theoretical Analysis

MedKoo Cat#: 600132
Name: Epicatechin gallate
CAS#: 1257-08-5
Chemical Formula: C22H18O10
Exact Mass: 442.09
Molecular Weight: 442.37
Elemental Analysis: C, 59.73; H, 4.10; O, 36.17

Price and Availability

Size Price Availability Quantity
5.0g USD 450.0 Same day
10.0g USD 850.0 Same day
100.0g USD 1850.0 Same day
200.0g USD 2850.0 Same day
1.0kg USD 4650.0 2 weeks
10.0kg USD 29750.0 2 weeks
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Synonym: ECG; Epicatechin 3-gallate; Epicatechin-3-O-gallate.

IUPAC/Chemical Name: [(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate

InChi Key: LSHVYAFMTMFKBA-TZIWHRDSSA-N

InChi Code: InChI=1S/C22H18O10/c23-11-6-14(25)12-8-19(32-22(30)10-4-16(27)20(29)17(28)5-10)21(31-18(12)7-11)9-1-2-13(24)15(26)3-9/h1-7,19,21,23-29H,8H2/t19-,21-/m1/s1

SMILES Code: O=C(O[C@H]1[C@@H](C2=CC=C(O)C(O)=C2)OC3=C(C(O)=CC(O)=C3)C1)C4=CC(O)=C(O)C(O)=C4

Appearance: Solid powder

Purity: >95% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO.

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 442.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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  1: Anderson JC, Grounds H, Reeves S, Taylor PW. Improved synthesis of structural   analogues of (-)-epicatechin gallate for modulation of staphylococcal β-lactam resistance. Tetrahedron. 2014 May 27;70(21):3485-3490. PubMed PMID: 24876661; PubMed Central PMCID: PMC4006114.