WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 600121
CAS#: 2415-24-9
Description: Catalpol is an iridoid glucoside. This natural product falls in the class of iridoid glycosides, which are simply monoterpenes with a glucose molecule attached. Although the pharmacological action of catalpol as well as many other iridoids has not been fully established, there is evidence that their primary function is to stimulate the production of adrenal cortical hormones, which increases the production of sex hormones. Catalpol also exhibits anti-inflammatory activity and has shown to increase the production of androgens yielded by the adrenal gland, which can lead to increases in muscle mass.
MedKoo Cat#: 600121
Name: Catalpol
CAS#: 2415-24-9
Chemical Formula: C15H22O10
Exact Mass: 362.1213
Molecular Weight: 362.33
Elemental Analysis: C, 49.72; H, 6.12; O, 44.16
Synonym: Catalpinoside
IUPAC/Chemical Name: (2S,3R,4S,5S,6R)-2-(((1aS,1bS,2S,5aR,6S,6aS)-6-hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[2',3':4,5]cyclopenta[1,2-c]pyran-2-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
InChi Key: LHDWRKICQLTVDL-PZYDOOQISA-N
InChi Code: InChI=1S/C15H22O10/c16-3-6-9(19)10(20)11(21)14(23-6)24-13-7-5(1-2-22-13)8(18)12-15(7,4-17)25-12/h1-2,5-14,16-21H,3-4H2/t5-,6-,7-,8+,9-,10+,11-,12+,13+,14+,15-/m1/s1
SMILES Code: [H][C@]1([C@H](O)[C@@]2([H])[C@]3(CO)O2)[C@]3([H])[C@H](O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)OC=C1
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO.
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 362.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Zhu H, Wan D, Zhang F. [Progress in studies of pharmacological action and mechanisms of catalpol on brain diease]. Zhongguo Zhong Yao Za Zhi. 2009 Dec;34(23):2983-6. Review. Chinese. PubMed PMID: 20222407.
2: Liu YF, Zhao Y, Wen XS, Dong QT. [Advances in research on pharmacodynamics and chemical conversion of catalpol]. Zhongguo Zhong Yao Za Zhi. 2007 Jun;32(12):1128-30. Review. Chinese. PubMed PMID: 17802867.
