Baicalin
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 600115

CAS#: 21967-41-9

Description: Baicalin is a flavone, a type of flavonoid. It is found in several species in the genus Scutellaria, including Scutellaria lateriflora (blue skullcap). There are 10 mg/g baicalin in Scutellaria galericulata (common skullcap) leaves. Baicalin is the glucuronide of baicalein. It is a component of Chinese medicinal herb Huang-chin (Scutellaria baicalensis) and one of the chemical ingredients of Sho-Saiko-To, an herbal supplement. Baicalin is a known prolyl endopeptidase inhibitor, induces apoptosis in pancreatic cancer cells, and affects the GABA receptors.


Price and Availability

Size
Price

1g
USD 170
Size
Price

2g
USD 200
Size
Price

Baicalin purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.


Chemical Structure

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Theoretical Analysis

MedKoo Cat#: 600115
Name: Baicalin
CAS#: 21967-41-9
Chemical Formula: C21H18O11
Exact Mass: 446.08491
Molecular Weight: 446.36
Elemental Analysis: C, 56.51; H, 4.06; O, 39.43p


Synonym:

IUPAC/Chemical Name: (2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenyl-chromen-7-yl)oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid

InChi Key: IKIIZLYTISPENI-ZFORQUDYSA-N

InChi Code: InChI=1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1

SMILES Code: O=C([C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC2=CC3=C(C(O)=C2O)C(C=C(C4=CC=CC=C4)O3)=O)O1)O


Technical Data

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO.

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

Harmonized System Code:
293490


References

1: Chai YS, Lei F, Xing DM, Ding Y, Du LJ. [Effect of baicalin on pattern recognition receptor TLR2/4-NOD2 and its significance of druggability]. Zhongguo Zhong Yao Za Zhi. 2013 Aug;38(16):2639-44. Review. Chinese. PubMed PMID: 24228579.

2: Sahebkar A. Baicalin as a potentially promising drug for the management of sulfur mustard induced cutaneous complications: a review of molecular mechanisms. Cutan Ocul Toxicol. 2012 Sep;31(3):226-34. doi: 10.3109/15569527.2011.633950. Epub 2011 Nov 22. Review. PubMed PMID: 22107027.

3: Srinivas NR. Baicalin, an emerging multi-therapeutic agent: pharmacodynamics, pharmacokinetics, and considerations from drug development perspectives. Xenobiotica. 2010 May;40(5):357-67. doi: 10.3109/00498251003663724. Review. PubMed PMID: 20230189.

4: Li-Weber M. New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin. Cancer Treat Rev. 2009 Feb;35(1):57-68. doi: 10.1016/j.ctrv.2008.09.005. Epub 2008 Nov 11. Review. PubMed PMID: 19004559.

5: Zhu Y. [The study on baicalin in China]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 1993 Sep;13(9):567-9. Review. Chinese. PubMed PMID: 8111218.