WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 510265
Description: ZLN005 is a PGC-1α Transcriptional Regulator, which shoed some beneficialfEffects on diabetic db/db mice. ZLN005 increased fat oxidation and improved the glucose tolerance, pyruvate tolerance, and insulin sensitivity of diabetic db/db mice. Hyperglycemia and dyslipidemia also were ameliorated after treatment with ZLN005. Our results demonstrated that a novel small molecule selectively elevated the expression of PGC-1α in myotubes and skeletal muscle and exerted promising therapeutic effects for treating type 2 diabetes.
MedKoo Cat#: 510265
Chemical Formula: C17H18N2
Exact Mass: 250.147
Molecular Weight: 250.33822
Elemental Analysis: C, 81.56; H, 7.25; N, 11.19
ZLN005, purity > 98%, is in stock. Same day shipping after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).
Synonym: ZLN005; ZLN-005; ZLN 005.
IUPAC/Chemical Name: 2-(4-(tert-butyl)phenyl)-1H-benzo[d]imidazole
InChi Key: LQUNNCQSFFKSSK-UHFFFAOYSA-N
InChi Code: InChI=1S/C17H18N2/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3,(H,18,19)
SMILES Code: CC(C1=CC=C(C2=NC3=CC=CC=C3N2)C=C1)(C)C
The following data is based on the product molecular weight 250.33822 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Zhang LN, Zhou HY, Fu YY, Li YY, Wu F, Gu M, Wu LY, Xia CM, Dong TC, Li JY, Shen JK, Li J. Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice. Diabetes. 2013 Apr;62(4):1297-307. doi: 10.2337/db12-0703. Epub 2012 Dec 18. PubMed PMID: 23250358; PubMed Central PMCID: PMC3609556.