ZLN005
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 510265

CAS#: 49671-76-3

Description: ZLN005 is a PGC-1α Transcriptional Regulator, which shoed some beneficialfEffects on diabetic db/db mice. ZLN005 increased fat oxidation and improved the glucose tolerance, pyruvate tolerance, and insulin sensitivity of diabetic db/db mice. Hyperglycemia and dyslipidemia also were ameliorated after treatment with ZLN005. Our results demonstrated that a novel small molecule selectively elevated the expression of PGC-1α in myotubes and skeletal muscle and exerted promising therapeutic effects for treating type 2 diabetes.


Chemical Structure

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ZLN005
CAS# 49671-76-3

Theoretical Analysis

MedKoo Cat#: 510265
Name: ZLN005
CAS#: 49671-76-3
Chemical Formula: C17H18N2
Exact Mass: 250.147
Molecular Weight: 250.33822
Elemental Analysis: C, 81.56; H, 7.25; N, 11.19

Size Price Shipping out time Quantity
10mg USD 150 2 Weeks
100mg USD 550 2 Weeks
500mg USD 750 2 Weeks
1g USD 1250 2 Weeks
2g USD 1950 2 Weeks
5g USD 3750 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-03-07. Prices are subject to change without notice.

ZLN005, purity > 98%, is in stock. Same day shipping after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).

Synonym: ZLN005; ZLN-005; ZLN 005.

IUPAC/Chemical Name: 2-(4-(tert-butyl)phenyl)-1H-benzo[d]imidazole

InChi Key: LQUNNCQSFFKSSK-UHFFFAOYSA-N

InChi Code: InChI=1S/C17H18N2/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3,(H,18,19)

SMILES Code: CC(C1=CC=C(C2=NC3=CC=CC=C3N2)C=C1)(C)C

Appearance:
white to off-white solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 250.33822 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Zhang LN, Zhou HY, Fu YY, Li YY, Wu F, Gu M, Wu LY, Xia CM, Dong TC, Li JY, Shen JK, Li J. Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice. Diabetes. 2013 Apr;62(4):1297-307. doi: 10.2337/db12-0703. Epub 2012 Dec 18. PubMed PMID: 23250358; PubMed Central PMCID: PMC3609556.



Additional Information