BMS303141
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 510276

CAS#: 943962-47-8

Description: BMS303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model.


Chemical Structure

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BMS303141
CAS# 943962-47-8

Theoretical Analysis

MedKoo Cat#: 510276
Name: BMS303141
CAS#: 943962-47-8
Chemical Formula: C19H15Cl2NO4S
Exact Mass: 423.00988
Molecular Weight: 424.2977
Elemental Analysis: C, 53.78; H, 3.56; Cl, 16.71; N, 3.30; O, 15.08; S, 7.56

Price and Availability

Size Price Availability Quantity
25.0mg USD 150.0 2 weeks
50.0mg USD 250.0 2 weeks
100.0mg USD 450.0 2 weeks
200.0mg USD 850.0 2 weeks
500.0mg USD 1650.0 2 weeks
1.0g USD 2650.0 2 weeks
2.0g USD 4450.0 2 weeks
5.0g USD 6850.0 2 weeks
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Synonym: BMS303141; BMS-303141; BMS 303141.

IUPAC/Chemical Name: 3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1′-biphenyl]-3-yl)-benzenesulfonamide

InChi Key: SIIPNDKXZOTLEA-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H15Cl2NO4S/c1-26-17-8-7-13(12-5-3-2-4-6-12)9-16(17)22-27(24,25)18-11-14(20)10-15(21)19(18)23/h2-11,22-23H,1H3

SMILES Code: O=S(C1=CC(Cl)=CC(Cl)=C1O)(NC2=CC(C3=CC=CC=C3)=CC=C2OC)=O

Appearance: white to off-white solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 424.2977 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Additional Information