WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 510339
CAS#: 101199-38-6 (sodium)
Description: PTZ-343 is a phenothiazine (PTZ) derivative with chemical name sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate. The free acid of PTZ-343 has molecule weight 343. For the convenience of commucation, we call it as PTZ-343. PTZ-343 is a water-soluble enhancer of luminol chemiluminescent peroxidation catalyzed by horseradish peroxidase (HRP). It acts as an electron transfer mediator, reacting with HRP-II to release HRP and a PTZ-343 radical, which oxidizes luminol anions to induce light emission.
MedKoo Cat#: 510339
CAS#: 101199-38-6 (sodium)
Chemical Formula: C15H14NNaO3S2
Molecular Weight: 343.39
Elemental Analysis: C, 52.46; H, 4.11; N, 4.08; Na, 6.69; O, 13.98; S, 18.68
PTZ-343 sodium is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 100 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to firstname.lastname@example.org to inquire quote.
Related CAS #: 101199-38-6 (sodium) 129808-92-0 (free acid)
Synonym: PTZ343; PTZ 343; PTZ-343; PTZ-343 sodium.
IUPAC/Chemical Name: sodium 3-(10H-phenothiazin-10-yl)propane-1-sulfonate
InChi Key: VKGYKXFNSKEHED-UHFFFAOYSA-M
InChi Code: InChI=1S/C15H15NO3S2.Na/c17-21(18,19)11-5-10-16-12-6-1-3-8-14(12)20-15-9-4-2-7-13(15)16;/h1-4,6-9H,5,10-11H2,(H,17,18,19);/q;+1/p-1
SMILES Code: O=S(CCCN1C2=C(C=CC=C2)SC3=CC=CC=C13)([O-])=O.[Na+]
The following data is based on the product molecular weight 343.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Marzocchi, E.,Grilli, S.,Della Ciana, L., et al. Chemiluminescent detection systems of horseradish peroxidase employing nucleophilic acylation catalysts. Anal. Biochem. 377(2), 189-194 (2008).
2. Vdovenko, M.M.,Della Ciana, L. and Sakharov, I.Y. 3-(100-Phenothiazinyl)propane-1-sulfonate is a potent enhancer of soybean peroxidase-induced chemiluminescence. Anal. Biochem. 392(1), 54-58 (2009).
3. Masato. Sakaguchi , Ming. Hu , Larry. Kevan. Photoionization of alkylphenothiazines in vesicles: effects of the alkyl chain length and the vesicle surface charge. J. Phys. Chem., 1990, 94 (2), pp 870Â–874.