Lacosamide

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 315229

CAS#: 175481-36-4

Description: Lacosamide, also known as ADD 243037 and SPM 927, is a medication developed by UCB for the adjunctive treatment of partial-onset seizures and diabetic neuropathic pain marketed under the trade name Vimpat. Lacosamide is discontinued (DEA controlled substance).


Chemical Structure

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Lacosamide
CAS# 175481-36-4

Theoretical Analysis

MedKoo Cat#: 315229
Name: Lacosamide
CAS#: 175481-36-4
Chemical Formula: C13H18N2O3
Exact Mass: 250.13174
Molecular Weight: 250.2
Elemental Analysis: C, 62.38; H, 7.25; N, 11.19; O, 19.18

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: Vimpat; erlosamide; ADD 243037; SPM 927; ADD243037; SPM927; ADD-243037; SPM-927.

IUPAC/Chemical Name: (R)-2-acetamido-N-benzyl-3-methoxypropionamide.

InChi Key: VPPJLAIAVCUEMN-GFCCVEGCSA-N

InChi Code: InChI=1S/C13H18N2O3/c1-10(16)15-12(9-18-2)13(17)14-8-11-6-4-3-5-7-11/h3-7,12H,8-9H2,1-2H3,(H,14,17)(H,15,16)/t12-/m1/s1

SMILES Code: O=C(NCC1=CC=CC=C1)[C@H](NC(C)=O)COC

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO.

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 250.2 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Hawkes MA, Fernández Suárez M, Ugarnes G, D'Giano C. Single-dose oral lacosamide in refractory simple partial status epilepticus: case report and review. Clin Neuropharmacol. 2013 Jul-Aug;36(4):138-40. doi: 10.1097/WNF.0b013e31829b21ba. Review. PubMed PMID: 23860347.