Ginsenoside Rb1

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 315132

CAS#: 41753-43-9

Description: Ginsenoside Rb1: appears to be most abundant in Panax quinquefolius (American Ginseng). Ginsenoside Rb1 seems to affect the reproductive system in animal testicles. Recent research shows that Ginsenoside Rb1 affects rat embryo development and has teratogenic effects, causing birth defects. Another study shows that Ginsenoside Rb1 may increase testosterone production in male rats indirectly through the stimulation of the luteinizing hormone. Traditional Chinese medicine asserts that Panax quinquefolius promotes yin in the body. Ginsenoside Rb1 also inhibits chemoinvasion and angiogenesis. (Source: )

Chemical Structure

Ginsenoside Rb1
CAS# 41753-43-9

Theoretical Analysis

MedKoo Cat#: 315132
Name: Ginsenoside Rb1
CAS#: 41753-43-9
Chemical Formula: C54H92O23
Exact Mass: 1108.60294
Molecular Weight: 1109.29
Elemental Analysis: C, 58.47; H, 8.36; O, 33.17

Price and Availability

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10.0mg USD 670.0 2 Weeks
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Synonym: (3beta12beta)20(6ObetaDGlucopyranosylbetaDglucopyranosyl)oxy12hydroxydammar24en3yl2ObetaDglucopyranosylbetaDglucopyranoside

IUPAC/Chemical Name: (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-4,5-dihydroxy-2-(((8R,10R,12S,13S,14S,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-((S)-6-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)hept-5-en-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol


InChi Code: InChI=1S/C54H92O23/c1-23(2)10-9-14-54(8,77-48-44(69)40(65)37(62)29(74-48)22-70-46-42(67)38(63)34(59)26(19-55)71-46)24-11-16-53(7)33(24)25(58)18-31-51(5)15-13-32(50(3,4)30(51)12-17-52(31,53)6)75-49-45(41(66)36(61)28(21-57)73-49)76-47-43(68)39(64)35(60)27(20-56)72-47/h10,24-49,55-69H,9,11-22H2,1-8H3/t24-,25-,26+,27+,28+,29+,30?,31?,32?,33+,34+,35+,36+,37+,38-,39-,40-,41-,42+,43+,44+,45+,46+,47-,48-,49-,51-,52+,53-,54-/m0/s1

SMILES Code: O[C@H]1[C@H](O[C@H]2[C@H](OC3CC[C@]4(C)C5C[C@H](O)[C@@]6([H])[C@@H]([C@](CC/C=C(C)\C)(O[C@H]7[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)O7)C)CC[C@]6(C)[C@]5(C)CCC4C3(C)C)O[C@H](CO)[C@@H](O)[C@@H]2O)O[C@H](CO)[C@@H](O)[C@@H]1O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO.

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 1109.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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 1: Shen L, Haas M, Wang DQ, May A, Lo CC, Obici S, Tso P, Woods SC, Liu M.
Ginsenoside Rb1 increases insulin sensitivity by activating AMP-activated protein
kinase in male rats. Physiol Rep. 2015 Sep;3(9). pii: e12543. doi:
10.14814/phy2.12543. PubMed PMID: 26359241.