Ganciclovir hydrate
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MedKoo CAT#: 315223

CAS#: 1359968-33-4 (hydrate)

Description: Ganciclovir (INN) is an antiviral medication used to treat or prevent cytomegalovirus (CMV) infections. Ganciclovir is a synthetic analogue of 2′-deoxy-guanosine. It is first phosphorylated to ganciclovir monophosphate by a viral kinase encoded by the cytomegalovirus (CMV) gene UL97 during infection. Subsequently, cellular kinases catalyze the formation of ganciclovir diphosphate and ganciclovir triphosphate, which is present in 10-fold greater concentrations in CMV or herpes simplex virus (HSV)-infected cells than uninfected cells. A prodrug form with improved oral bioavailability (valganciclovir) has also been developed.


Chemical Structure

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Ganciclovir hydrate
CAS# 1359968-33-4 (hydrate)

Theoretical Analysis

MedKoo Cat#: 315223
Name: Ganciclovir hydrate
CAS#: 1359968-33-4 (hydrate)
Chemical Formula: C9H15N5O5
Exact Mass:
Molecular Weight: 273.25
Elemental Analysis: C, 39.56; H, 5.53; N, 25.63; O, 29.28

Price and Availability

Size Price Availability Quantity
1.0g USD 90.0 Same day
10.0g USD 190.0 2 weeks
20.0g USD 350.0 2 weeks
50.0g USD 750.0 2 weeks
100.0g USD 1250.0 2 weeks
200.0g USD 2250.0 2 weeks
500.0g USD 3450.0 2 weeks
1.0kg USD 4950.0 2 weeks
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Related CAS #: 82410-32-0 (free)   1359968-33-4 (hydrate)   84245-13-6 (x sodium)   107910-75-8 (sodium)   352346-23-7 (potassium)    

Synonym: BW-759; BW 759; BW759; BIOLF-62; RS-21592; RS 21592; RS21592; Ganciclovir; Ganciclovir Sodium; Ganciclovir Monosodium Salt; Gancyclovir; brand name: Cytovene; Cymevene; Vitrasert.

IUPAC/Chemical Name: 2-amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-3H-purin-6(9H)-one hydrate

InChi Key: KLXHZXWXXKSKRU-UHFFFAOYSA-N

InChi Code: InChI=1S/C9H13N5O4.H2O/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16;/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17);1H2

SMILES Code: O=C1N=C(N)NC2=C1N=CN2COC(CO)CO.[H]O[H]

Appearance: White to off-white solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO.

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Certificate of Analysis:

Safety Data Sheet (SDS):

Preparing Stock Solutions

The following data is based on the product molecular weight 273.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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