WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 315223
Description: Ganciclovir (INN) is an antiviral medication used to treat or prevent cytomegalovirus (CMV) infections. Ganciclovir is a synthetic analogue of 2′-deoxy-guanosine. It is first phosphorylated to ganciclovir monophosphate by a viral kinase encoded by the cytomegalovirus (CMV) gene UL97 during infection. Subsequently, cellular kinases catalyze the formation of ganciclovir diphosphate and ganciclovir triphosphate, which is present in 10-fold greater concentrations in CMV or herpes simplex virus (HSV)-infected cells than uninfected cells. A prodrug form with improved oral bioavailability (valganciclovir) has also been developed.
MedKoo Cat#: 315223
Name: Ganciclovir hydrate
Chemical Formula: C9H15N5O5
Molecular Weight: 273.25
Elemental Analysis: C, 39.56; H, 5.53; N, 25.63; O, 29.28
Synonym: BW-759; BW 759; BW759; BIOLF-62; RS-21592; RS 21592; RS21592; Ganciclovir; Ganciclovir Sodium; Ganciclovir Monosodium Salt; Gancyclovir; brand name: Cytovene; Cymevene; Vitrasert.
IUPAC/Chemical Name: 2-amino-9-(((1,3-dihydroxypropan-2-yl)oxy)methyl)-3H-purin-6(9H)-one hydrate
InChi Key: KLXHZXWXXKSKRU-UHFFFAOYSA-N
InChi Code: InChI=1S/C9H13N5O4.H2O/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16;/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17);1H2
SMILES Code: O=C1N=C(N)NC2=C1N=CN2COC(CO)CO.[H]O[H]