Fluorogestone acetate
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MedKoo CAT#: 315130

CAS#: 2529-45-5

Description: Fluorogestone Acetate (also known as Flurogestone Acetate, Flugestone Acetate, Fluorogesterone Acetate) was first synthesised by G. D. Searle and Company in 1959. The chemical, which has progestogen activity, was identified as SC-9880. Fluorogestone acetate showed a high potency with short duration of activity and performed physiologically similar to progesterone. FGA was approximately 20 – 25 times more potent than progesterone. Flurogestone acetate was shown to be readily absorbed from impregnated sponges. A 30mg impregnated sponge was effective in blocking ovulation and oestrus, once the sponge was removed impregnated ewes showed visible oestrus, and if inseminated 2 to 4 days after sponge removal showed high conception rates. (Source: http://pharmplex.com.au/Technical/fluorogestone_acetate_sheep_goat.htm).


Chemical Structure

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Fluorogestone acetate
CAS# 2529-45-5

Theoretical Analysis

MedKoo Cat#: 315130
Name: Fluorogestone acetate
CAS#: 2529-45-5
Chemical Formula: C23H31FO5
Exact Mass: 406.21555
Molecular Weight: 406.49
Elemental Analysis: C, 67.96; H, 7.69; F, 4.67; O, 19.68

Price and Availability

Size Price Availability Quantity
10.0mg USD 350.0 2 Weeks
25.0mg USD 650.0 2 Weeks
50.0mg USD 1050.0 2 Weeks
100.0mg USD 1850.0 2 Weeks
200.0mg USD 2950.0 2 Weeks
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Synonym: Flurogestone Acetate Flugestone Acetate Fluorogesterone Acetate SC9880.

IUPAC/Chemical Name: (8S,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate

InChi Key: JKQQZJHNUVDHKP-VIIVLCOPSA-N

InChi Code: InChI=1S/C23H31FO5/c1-13(25)22(29-14(2)26)10-8-17-18-6-5-15-11-16(27)7-9-20(15,3)23(18,24)19(28)12-21(17,22)4/h11,17-19,28H,5-10,12H2,1-4H3/t17-,18-,19-,20-,21-,22-,23?/m0/s1

SMILES Code: CC(O[C@]1(C(C)=O)CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)C3(F)[C@@H](O)C[C@]12C)=O)=O

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO.

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 406.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Quintero-Elisea JA, Macías-Cruz U, Ã