Cefsulodine sodium
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 315129

CAS#: 52152-93-9 (salt)

Description: Cefsulodin sodium is a narrow-spectrum cephalosporin with marked in vitro activity against clinical isolates of Pseudomonas aeruginosa.


Chemical Structure

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Cefsulodine sodium
CAS# 52152-93-9 (salt)

Theoretical Analysis

MedKoo Cat#: 315129
Name: Cefsulodine sodium
CAS#: 52152-93-9 (salt)
Chemical Formula: C22H19N4NaO8S2
Exact Mass:
Molecular Weight: 554.53
Elemental Analysis: C, 47.65; H, 3.45; N, 10.10; Na, 4.15; O, 23.08; S, 11.56

Size Price Shipping out time Quantity
100mg USD 210 2 Weeks
250mg USD 345 2 Weeks
500mg USD 550 2 Weeks
1g USD 730 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-03-05. Prices are subject to change without notice.

Cefsulodine sodium, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received.

Related CAS #: 62587-73-9 (free base)   52152-93-9 (salt)  

Synonym: Sodium (6R7R)3(4carbamoylpyridin1ium1yl)methyl8oxo7(2R)2phenyl2sulfonatoacetylamino5thia1azabicyclo4.2.0oct2ene2carboxylate

IUPAC/Chemical Name: sodium (6R,7R)-3-((4-carbamoylpyridin-1-ium-1-yl)methyl)-8-oxo-7-((R)-2-phenyl-2-sulfonatoacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

InChi Key: REACMANCWHKJSM-DWBVFMGKSA-M

InChi Code: InChI=1S/C22H20N4O8S2.Na/c23-18(27)13-6-8-25(9-7-13)10-14-11-35-21-15(20(29)26(21)16(14)22(30)31)24-19(28)17(36(32,33)34)12-4-2-1-3-5-12;/h1-9,15,17,21H,10-11H2,(H4-,23,24,27,28,30,31,32,33,34);/q;+1/p-1/t15-,17-,21-;/m1./s1

SMILES Code: O=C(C(N12)=C(C[N+]3=CC=C(C(N)=O)C=C3)CS[C@]2([H])[C@H](NC([C@@H](C4=CC=CC=C4)S(=O)([O-])=O)=O)C1=O)[O-].[Na+]

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO.

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Handling Instructions:

Preparing Stock Solutions

The following data is based on the product molecular weight 554.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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 1: Kocaoglu O, Tsui HC, Winkler ME, Carlson EE. Profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39. Antimicrob Agents Chemother. 2015 Jun;59(6):3548-55. doi: 10.1128/AAC.05142-14. Epub 2015 Apr 6. PubMed PMID: 25845878; PubMed Central PMCID: PMC4432181.

2: Liu W, Zhao XM, Zhang HB, Zhang L, Zhao MZ. Asymmetric synthesis of allylic sulfonic acids: enantio- and regioselective iridium-catalyzed allylations of Na2SO3. Chemistry. 2014 Dec 15;20(51):16873-6. doi: 10.1002/chem.201405058. Epub 2014 Nov 3. PubMed PMID: 25367779.

3: Miller OJ, El Harrak A, Mangeat T, Baret JC, Frenz L, El Debs B, Mayot E, Samuels ML, Rooney EK, Dieu P, Galvan M, Link DR, Griffiths AD. High-resolution dose-response screening using droplet-based microfluidics. Proc Natl Acad Sci U S A. 2012 Jan 10;109(2):378-83. doi: 10.1073/pnas.1113324109. Epub 2011 Dec 27. PubMed PMID: 22203966; PubMed Central PMCID: PMC3258639.

4: Nakakariya M, Shimada T, Irokawa M, Koibuchi H, Iwanaga T, Yabuuchi H, Maeda T, Tamai I. Predominant contribution of rat organic anion transporting polypeptide-2 (Oatp2) to hepatic uptake of beta-lactam antibiotics. Pharm Res. 2008 Mar;25(3):578-85. Epub 2007 Sep 22. PubMed PMID: 17891554.

5: Tokunaga H, Mitsuo K, Ichinose S, Omori A, Ventosa A, Nakae T, Tokunaga M. Salt-inducible multidrug efflux pump protein in the moderately halophilic bacterium Chromohalobacter sp. Appl Environ Microbiol. 2004 Aug;70(8):4424-31. PubMed PMID: 15294769; PubMed Central PMCID: PMC492394.

6: Stephens PJ, Joynson JA. Direct inoculation into media containing bile salts and antibiotics is unsuitable for the detection of acid/salt stressed Escherichia coli O157:H7. Lett Appl Microbiol. 1998 Sep;27(3):147-51. PubMed PMID: 9750318.

7: Gorski RJ, Plasz AC, Elrod L Jr, Yoder J, White LB. Determination of cefsulodin, cefmenoxime, and cefadroxil as residues on surfaces. Pharm Res. 1991 Dec;8(12):1525-7. PubMed PMID: 1808618.

8: Cohen MA, Huband MD, Mailloux GB, Yoder SL, Roland GE, Heifetz CL. In vitro antibacterial activities of the fluoroquinolones PD 117596, PD 124816, and PD 127391. Diagn Microbiol Infect Dis. 1991 May-Jun;14(3):245-58. PubMed PMID: 1889177.

9: Wright DN, Marble DA, Saxon B, Johnson CC, Bosso JA, Matsen JM. In vitro inactivation of aminoglycosides by cephalosporin antibiotics. Arch Pathol Lab Med. 1988 May;112(5):526-8. PubMed PMID: 3358654.

10: Singh A, McFeters GA. Survival and virulence of copper- and chlorine-stressed Yersinia enterocolitica in experimentally infected mice. Appl Environ Microbiol. 1987 Aug;53(8):1768-74. PubMed PMID: 3662514; PubMed Central PMCID: PMC203994.