WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 315283
Description: Bethanechol chloride, a cholinergic agent, is a synthetic esler which is structurally and pharmacologically related to acetylcholine. It is designated chemically as Z-[(aminocarbony) oxy]-N, N, (V-trimethyl-1-propanaminium chloride. Its molecular formula is C7H17CIN202. It is a white, hygroscopic crystalline powder having a slight amine-like odor, freely soluble in water, and has a molecular weight of 196.68. Each tablet for oral administration contains 5 mg, 10 mg, 25 mg or 50 mg bethanechol chloride, USP Tablets also contain the following inactive ingredients: colloidal silicon dioxide, lactose monohydrate, magnesium stearate, microcrystalline cellulose, sodium starch glycolate, (25 mg and 50 mg) D&C~ Yellow # 10 Lake and FD&C Yellow # 6 Lake.
MedKoo Cat#: 315283
Name: Bethanechol Chloride
Chemical Formula: C7H17ClN2O2
Exact Mass: 196.1
Molecular Weight: 196.68
Elemental Analysis: C, 42.75; H, 8.71; Cl, 18.03; N, 14.24; O, 16.27
IUPAC/Chemical Name: 2-(carbamoyloxy)-N,N,N-trimethylpropan-1-aminium chloride
InChi Key: XXRMYXBSBOVVBH-UHFFFAOYSA-N
InChi Code: InChI=1S/C7H16N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H-,8,10);1H
SMILES Code: CC(OC(N)=O)C[N+](C)(C)C.[Cl-]
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO.
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 196.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
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2: Liu L, Rittenhouse AR. Pharmacological discrimination between muscarinic receptor signal transduction cascades with bethanechol chloride. Br J Pharmacol. 2003 Apr;138(7):1259-70. PubMed PMID: 12711626; PubMed Central PMCID: PMC1573771.
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6: Taillandier J, Boiteux JP, Boyer L, Guy L, Giraud B. Re: Detection of missing vesicoureteral reflux with bethanechol chloride-aided voiding cystourethrography. J Urol. 1993 Apr;149(4):867-8. PubMed PMID: 8095993.
7: Araki T, Nakano S, Sugimura Y, Tochigi H, Kawamura J, Kato T, Tajima K, Chigusa I, Saito K, Morisita H, et al. [Efficacy of combination of Ea-0643 (bunazosin hydrochloride) and bethanechol chloride in patients with neurogenic bladder]. Hinyokika Kiyo. 1990 Nov;36(11):1379-83. Japanese. PubMed PMID: 1981126.
8: Harbaugh RE, Reeder TM, Senter HJ, Knopman DS, Baskin DS, Pirozzolo F, Chui HC, Shetter AG, Bakay RA, Leblanc R, et al. Intracerebroventricular bethanechol chloride infusion in Alzheimer's disease. Results of a collaborative double-blind study. J Neurosurg. 1989 Oct;71(4):481-6. PubMed PMID: 2571689.
9: Koyanagi T, Morita H, Gotoh T, Nonomura K, Togashi M, Nantani M. Detection of missing vesicoureteral reflux with bethanechol chloride-aided voiding cystourethrography. J Urol. 1989 Mar;141(3):580-2. PubMed PMID: 2563779.
10: Zgourides GD. Bethanechol chloride as a suggested adjunct to prolonged in vivo exposure therapy in the treatment of paruresis. Percept Mot Skills. 1988 Feb;66(1):319-22. PubMed PMID: 2896331.