WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406365
CAS#: 1062159-35-6
Description: WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM.
MedKoo Cat#: 406365
Name: WAY-600
CAS#: 1062159-35-6
Chemical Formula: C28H30N8O
Exact Mass: 494.25426
Molecular Weight: 494.5908
Elemental Analysis: C, 68.00; H, 6.11; N, 22.66; O, 3.23
WAY-600, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received..
Synonym: WAY600; WAY 600; WAY600.
IUPAC/Chemical Name: 4-(6-(1H-indol-5-yl)-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)morpholine
InChi Key: FPEIJQLXFHKLJV-UHFFFAOYSA-N
InChi Code: InChI=1S/C28H30N8O/c1-2-20(17-29-8-1)19-34-10-6-23(7-11-34)36-28-24(18-31-36)27(35-12-14-37-15-13-35)32-26(33-28)22-3-4-25-21(16-22)5-9-30-25/h1-5,8-9,16-18,23,30H,6-7,10-15,19H2
SMILES Code: N1(C2=C3C(N(C4CCN(CC5=CC=CN=C5)CC4)N=C3)=NC(C6=CC7=C(NC=C7)C=C6)=N2)CCOCC1
The following data is based on the product molecular weight 494.5908 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Yu K, Toral-Barza L, Shi C, Zhang WG, Lucas J, Shor B, Kim J, Verheijen J, Curran K, Malwitz DJ, Cole DC, Ellingboe J, Ayral-Kaloustian S, Mansour TS, Gibbons JJ, Abraham RT, Nowak P, Zask A. Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin. Cancer Res. 2009 Aug 1;69(15):6232-40. doi: 10.1158/0008-5472.CAN-09-0299. Epub 2009 Jul 7. PubMed PMID: 19584280.