WAY-600
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406365

CAS#: 1062159-35-6

Description: WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM.


Chemical Structure

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WAY-600
CAS# 1062159-35-6

Theoretical Analysis

MedKoo Cat#: 406365
Name: WAY-600
CAS#: 1062159-35-6
Chemical Formula: C28H30N8O
Exact Mass: 494.25426
Molecular Weight: 494.5908
Elemental Analysis: C, 68.00; H, 6.11; N, 22.66; O, 3.23

Price and Availability

Size Price Availability Quantity
5.0mg USD 400.0 2 Weeks
10.0mg USD 700.0 2 Weeks
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Synonym: WAY600; WAY 600; WAY600.

IUPAC/Chemical Name: 4-(6-(1H-indol-5-yl)-1-(1-(pyridin-3-ylmethyl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)morpholine

InChi Key: FPEIJQLXFHKLJV-UHFFFAOYSA-N

InChi Code: InChI=1S/C28H30N8O/c1-2-20(17-29-8-1)19-34-10-6-23(7-11-34)36-28-24(18-31-36)27(35-12-14-37-15-13-35)32-26(33-28)22-3-4-25-21(16-22)5-9-30-25/h1-5,8-9,16-18,23,30H,6-7,10-15,19H2

SMILES Code: N1(C2=C3C(N(C4CCN(CC5=CC=CN=C5)CC4)N=C3)=NC(C6=CC7=C(NC=C7)C=C6)=N2)CCOCC1

Appearance: White solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 494.5908 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Yu K, Toral-Barza L, Shi C, Zhang WG, Lucas J, Shor B, Kim J, Verheijen J, Curran K, Malwitz DJ, Cole DC, Ellingboe J, Ayral-Kaloustian S, Mansour TS, Gibbons JJ, Abraham RT, Nowak P, Zask A. Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin. Cancer Res. 2009 Aug 1;69(15):6232-40. doi: 10.1158/0008-5472.CAN-09-0299. Epub 2009 Jul 7. PubMed PMID: 19584280.

WAY-600

5.0mg / USD 400.0


Additional Information