WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406143
Description: VPC03090 is a Sphingosine-1-Phosphate Receptor Inhibitor. VPC03090 is an analog of FTY-720, acts as antagonist for S1PR1 and S1PR3. VPC03090-P, converted from VPC03090 through the phosphorylation by SK-2, causes a reduction in tumor growth in mice with mammary cancer, and its oral bioavailability is determined to be 30 hours.
MedKoo Cat#: 406143
Chemical Formula: C19H31NO
Exact Mass: 289.2406
Molecular Weight: 289.463
Elemental Analysis: C, 78.84; H, 10.80; N, 4.84; O, 5.53
VPC03090 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to email@example.com to inquire quote.
Synonym: VPC03090, VPC 03090, VPC-03090
IUPAC/Chemical Name: (1-amino-3-(3-octylphenyl)cyclobutyl)methanol
InChi Key: FXTVJTIVYXHEBU-UHFFFAOYSA-N
InChi Code: InChI=1S/C19H31NO/c1-2-3-4-5-6-7-9-16-10-8-11-17(12-16)18-13-19(20,14-18)15-21/h8,10-12,18,21H,2-7,9,13-15,20H2,1H3
SMILES Code: OCC1(N)CC(C2=CC=CC(CCCCCCCC)=C2)C1
The following data is based on the product molecular weight 289.463 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Kennedy PC, Zhu R, Huang T, Tomsig JL, Mathews TP, David M, Peyruchaud O, Macdonald TL, Lynch KR. Characterization of a sphingosine 1-phosphate receptor antagonist prodrug. J Pharmacol Exp Ther. 2011 Sep;338(3):879-89. doi: 10.1124/jpet.111.181552. PubMed PMID: 21632869; PubMed Central PMCID: PMC3164350.