WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 403010
Description: TG100713 is an inhibitor of PI3-kinase that inhibits endothelial cell proliferation.
MedKoo Cat#: 403010
Chemical Formula: C12H10N6O
Exact Mass: 254.09161
Molecular Weight: 254.25
Elemental Analysis: C, 56.69; H, 3.96; N, 33.05; O, 6.29
TG100713, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).
Synonym: TG100713; TG 100713; TG-100713
IUPAC/Chemical Name: 3-(2,4-diaminopteridin-6-yl)phenol
InChi Key: UOORQSPLBHUQDQ-UHFFFAOYSA-N
InChi Code: InChI=1S/C12H10N6O/c13-10-9-11(18-12(14)17-10)15-5-8(16-9)6-2-1-3-7(19)4-6/h1-5,19H,(H4,13,14,15,17,18)
SMILES Code: OC1=CC=CC(C2=NC3=C(N)N=C(N)N=C3N=C2)=C1
The following data is based on the product molecular weight 254.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1. Doukas, J., Wrasidlo, W., Noronha, G., et al. Phosphoinositide 3-kinase γ/δ inhibition limits infarct size after myocardial ischemia/reperfusion injury. Proc. Natl. Acad. Sci. USA 103(52), 19866-19871 (2006).
2. Vargas, B., Giacobbi, N.S., Sanyal, A., et al. Inhibitors of signaling pathways that block reversal of HIV-1 latency. Antimicrob. Agents Chemother. 63(2), e01744-01718 (2019).