WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406159
CAS#: 701976-54-7
Description:
MedKoo Cat#: 406159
Name: SH-5
CAS#: 701976-54-7
Chemical Formula: C29H59O10P
Exact Mass: 598.38458
Molecular Weight: 598.74652
Elemental Analysis: C, 58.17; H, 9.93; O, 26.72; P, 5.17
Optional 3: SH-5 , purity > 98%, is not in stock, may be available through custom synthesis. Minimum 1 gram order is requested. Current shipping out time is about 70 days after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: $30.00 (USA); from $45.00 (Canada); from $70.00 (international).
Synonym: SH5 PIA5. LchiroInositol 1deoxy6Omethyl 5(2R)2methoxy3(octadecyloxy)propyl hydrogen phosphate. Akt inhibitor II.
IUPAC/Chemical Name: (R)-2-methoxy-3-(octadecyloxy)propyl ((1S,2R,3S,4R,6R)-2,3,4-trihydroxy-6-methoxycyclohexyl) hydrogen phosphate
InChi Key: NRLLDDPUQZQEDV-MWJQJBPESA-N
InChi Code: InChI=1S/C29H59O10P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-37-22-24(35-2)23-38-40(33,34)39-29-26(36-3)21-25(30)27(31)28(29)32/h24-32H,4-23H2,1-3H3,(H,33,34)/t24-,25-,26-,27+,28-,29-/m1/s1
SMILES Code: O=P(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)C[C@H]1OC)(OC[C@H](OC)COCCCCCCCCCCCCCCCCCC)O
The following data is based on the product molecular weight 598.74652 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1: Krech T, Thiede M, Hilgenberg E, Schäfer R, Jürchott K. Characterization of AKT independent effects of the synthetic AKT inhibitors SH-5 and SH-6 using an integrated approach combining transcriptomic profiling and signaling pathway perturbations. BMC Cancer. 2010 Jun 14;10:287. doi: 10.1186/1471-2407-10-287. PubMed PMID: 20546605; PubMed Central PMCID: PMC2895615.