WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406225

CAS#: 104408-38-0

Description: SC-44463 is an MMP inhibitor, also a collagenase inhibitor , and HDAC inhibitor.

Chemical Structure

CAS# 104408-38-0

Theoretical Analysis

MedKoo Cat#: 406225
Name: SC-44463
CAS#: 104408-38-0
Chemical Formula: C19H29N3O5
Exact Mass: 379.21072
Molecular Weight: 379.45
Elemental Analysis: C, 60.14; H, 7.70; N, 11.07; O, 21.08

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: SC44463; SC44463; SC 44463.

IUPAC/Chemical Name: (R)-N4-hydroxy-2-isobutyl-N1-((S)-3-(4-methoxyphenyl)-1-(methylamino)-1-oxopropan-2-yl)succinamide


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >5 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 379.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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7: Zhang D, Botos I, Gomis-Rüth FX, Doll R, Blood C, Njoroge FG, Fox JW, Bode W, Meyer EF. Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d). Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8447-51. PubMed PMID: 8078901; PubMed Central PMCID: PMC44623.

8: Boghaert ER, Chan SK, Zimmer C, Grobelny D, Galardy RE, Vanaman TC, Zimmer SG. Inhibition of collagenolytic activity relates to quantitative reduction of invasion in vitro in a c-Ha-ras transfected glial cell line. J Neurooncol. 1994;21(2):141-50. PubMed PMID: 7861190.

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10: Fini ME, Cui TY, Mouldovan A, Grobelny D, Galardy RE, Fisher SJ. An inhibitor of the matrix metalloproteinase synthesized by rabbit corneal epithelium. Invest Ophthalmol Vis Sci. 1991 Oct;32(11):2997-3001. PubMed PMID: 1655675

Additional Information