WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406338
CAS#: 218160-26-0
Description: RPR203494 is a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency.
MedKoo Cat#: 406338
Name: RPR203494
CAS#: 218160-26-0
Chemical Formula: C26H29FN6O4
Exact Mass: 508.22343
Molecular Weight: 508.54
Elemental Analysis: C, 61.41; H, 5.75; F, 3.74; N, 16.53; O, 12.58
RPR203494 is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.
Synonym: RPR203494; RPR203494; RPR 203494.
IUPAC/Chemical Name: ((2r,5r)-2-(5-(2-(cyclopropylamino)pyrimidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-2-yl)-5-methyl-1,3-dioxan-5-yl)(morpholino)methanone
InChi Key: RERSCSYZEKLVHG-OJBMAJLDSA-N
InChi Code: InChI=1S/C26H29FN6O4/c1-26(24(34)33-10-12-35-13-11-33)14-36-23(37-15-26)22-31-20(16-2-4-17(27)5-3-16)21(32-22)19-8-9-28-25(30-19)29-18-6-7-18/h2-5,8-9,18,23H,6-7,10-15H2,1H3,(H,31,32)(H,28,29,30)/t23-,26-
SMILES Code: O=C([C@]1(C)CO[C@@H](C2=NC(C3=CC=C(F)C=C3)=C(C4=NC(NC5CC5)=NC=C4)N2)OC1)N6CCOCC6
The following data is based on the product molecular weight 508.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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