WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406338
CAS#: 218160-26-0
Description: RPR203494 is a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency.
MedKoo Cat#: 406338
Name: RPR203494
CAS#: 218160-26-0
Chemical Formula: C26H29FN6O4
Exact Mass: 508.22343
Molecular Weight: 508.54
Elemental Analysis: C, 61.41; H, 5.75; F, 3.74; N, 16.53; O, 12.58
This product is not in stock, which may be available by custom synthesis.
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Synonym: RPR203494; RPR203494; RPR 203494.
IUPAC/Chemical Name: ((2r,5r)-2-(5-(2-(cyclopropylamino)pyrimidin-4-yl)-4-(4-fluorophenyl)-1H-imidazol-2-yl)-5-methyl-1,3-dioxan-5-yl)(morpholino)methanone
InChi Key: RERSCSYZEKLVHG-OJBMAJLDSA-N
InChi Code: InChI=1S/C26H29FN6O4/c1-26(24(34)33-10-12-35-13-11-33)14-36-23(37-15-26)22-31-20(16-2-4-17(27)5-3-16)21(32-22)19-8-9-28-25(30-19)29-18-6-7-18/h2-5,8-9,18,23H,6-7,10-15H2,1H3,(H,31,32)(H,28,29,30)/t23-,26-
SMILES Code: O=C([C@]1(C)CO[C@@H](C2=NC(C3=CC=C(F)C=C3)=C(C4=NC(NC5CC5)=NC=C4)N2)OC1)N6CCOCC6
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs
Storage Condition: 0 – 4 oC for short term (weeks to 1 month) or -20 oC for long terms (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly.
Drug Formulation: Stock solution storage:
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 508.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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