WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406515

CAS#: 157254-60-9

Description: PBIT is a potent inhibitor of iNOS and nNOS with Ki values of 7.4 and 16 nM, respectively. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.

Chemical Structure

CAS# 157254-60-9

Theoretical Analysis

MedKoo Cat#: 406515
Name: PBIT
CAS#: 157254-60-9
Chemical Formula:
Exact Mass:
Molecular Weight:
Elemental Analysis:

Price and Availability

Size Price Availability Quantity
10.0mg USD 160.0 2 Weeks
50.0mg USD 300.0 2 Weeks
100.0mg USD 550.0 2 Weeks
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Synonym: PBIT

IUPAC/Chemical Name: S,S'-1,4-phenylenebis(1,2-ethanediyl)bis-isothiourea


InChi Code: InChI=1S/C12H18N4S2/c13-11(14)17-7-5-9-1-2-10(4-3-9)6-8-18-12(15)16/h1-4H,5-8H2,(H3,13,14)(H3,15,16)


Appearance: white solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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10.0mg / USD 160.0

Additional Information