ISC-4

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406157

CAS#: 1072807-15-8

Description: ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.


Chemical Structure

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ISC-4
CAS# 1072807-15-8

Theoretical Analysis

MedKoo Cat#: 406157
Name: ISC-4
CAS#: 1072807-15-8
Chemical Formula: C11H13NSe
Exact Mass: 239.02132
Molecular Weight: 238.19
Elemental Analysis: C, 55.47; H, 5.50; N, 5.88; Se, 33.15

Size Price Shipping out time Quantity
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Pricing updated 2021-03-08. Prices are subject to change without notice.

ISC-4 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Synonym: ISC4, ISC-4, ISC 4

IUPAC/Chemical Name: (4-isoselenocyanatobutyl)benzene

InChi Key: NMPQIJIERCLTOG-UHFFFAOYSA-N

InChi Code: InChI=1S/C11H13NSe/c13-10-12-9-5-4-8-11-6-2-1-3-7-11/h1-3,6-7H,4-5,8-9H2

SMILES Code: [Se]=C=NCCCCC1=CC=CC=C1

Appearance:
Solid powder

Purity:
>98%

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>5 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Handling Instructions:

Preparing Stock Solutions

The following data is based on the product molecular weight 238.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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 1: Sharma AK, Kline CL, Berg A, Amin S, Irby RB. The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model. Clin Cancer Res. 2011 Jul 1;17(13):4474-83. doi: 10.1158/1078-0432.CCR-10-2370. Epub 2011 May 9. PubMed PMID: 21555373; PubMed Central PMCID: PMC3131476.

ISC-4

10mg / Not available


Additional Information