WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406157
Description: ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.
MedKoo Cat#: 406157
Chemical Formula: C11H13NSe
Exact Mass: 239.02132
Molecular Weight: 238.19
Elemental Analysis: C, 55.47; H, 5.50; N, 5.88; Se, 33.15
ISC-4 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to firstname.lastname@example.org to inquire quote.
Synonym: ISC4, ISC-4, ISC 4
IUPAC/Chemical Name: (4-isoselenocyanatobutyl)benzene
InChi Key: NMPQIJIERCLTOG-UHFFFAOYSA-N
InChi Code: InChI=1S/C11H13NSe/c13-10-12-9-5-4-8-11-6-2-1-3-7-11/h1-3,6-7H,4-5,8-9H2
SMILES Code: [Se]=C=NCCCCC1=CC=CC=C1
The following data is based on the product molecular weight 238.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Sharma AK, Kline CL, Berg A, Amin S, Irby RB. The Akt inhibitor ISC-4 activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model. Clin Cancer Res. 2011 Jul 1;17(13):4474-83. doi: 10.1158/1078-0432.CCR-10-2370. Epub 2011 May 9. PubMed PMID: 21555373; PubMed Central PMCID: PMC3131476.