G3130

    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406499

CAS#: 848952-37-4

Description: G3130 is a reversible Hsp90 inhibitor with potential anticancer activity. G3130 demonstrated cellular activities (in Her-2 degradation and activation of Hsp70 promoter) consistent with the inhibition of cellular Hsp90 functions.

Chemical Structure

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G3130
CAS# 848952-37-4
Handing Instruction

Theoretical Analysis

MedKoo Cat#: 406499
Name: G3130
CAS#: 848952-37-4
Chemical Formula: C14H14N4O2
Exact Mass: 270.11168
Molecular Weight: 270.28656
Elemental Analysis: C, 62.21; H, 5.22; N, 20.73; O, 11.84

Size Price Shipping out time Quantity
Inquire bulk and customized quantity
Pricing updated 2021-02-27. Prices are subject to change without notice.

G3130 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Synonym: G3130; G-3130; G 3130

IUPAC/Chemical Name: 4-(4-(1H-imidazol-4-yl)-1H-pyrazol-3-yl)-6-ethylbenzene-1,3-diol

InChi Key: ATORUNMAUREKMH-UHFFFAOYSA-N

InChi Code: InChI=1S/C14H14N4O2/c1-2-8-3-9(13(20)4-12(8)19)14-10(5-17-18-14)11-6-15-7-16-11/h3-7,19-20H,2H2,1H3,(H,15,16)(H,17,18)

SMILES Code: OC1=C(CC)C=C(C2=NNC=C2C3=CNC=N3)C(O)=C1

Appearance:
white solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Handling Instructions:
View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 270.28656 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Reconstitution Calculator

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1: Shen G, Blagg BS. Radester, a novel inhibitor of the Hsp90 protein folding machinery. Org Lett. 2005 May 26;7(11):2157-60. PubMed PMID: 15901158.

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G3130



Additional Information