WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406199
Description: CInQ-03 is a novel and specific MEK inhibitor both in vitro and in vivo.
MedKoo Cat#: 406199
Chemical Formula: C22H12ClN5O
Exact Mass: 397.07304
Molecular Weight: 397.82
Elemental Analysis: C, 66.42; H, 3.04; Cl, 8.91; N, 17.60; O, 4.02
CInQ-03, purity > 98% is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to email@example.com to inquire quote.
IUPAC/Chemical Name: 2-chloro-N-(12-cyanoindolizino[2,3-b]quinoxalin-2-yl)benzamide
InChi Key: HLFGQICCFZTXTP-UHFFFAOYSA-N
InChi Code: InChI=1S/C22H12ClN5O/c23-16-6-2-1-5-14(16)22(29)25-13-9-10-28-19(11-13)15(12-24)20-21(28)27-18-8-4-3-7-17(18)26-20/h1-11H,(H,25,29)
SMILES Code: O=C(NC1=CC2=C(C#N)C3=NC4=CC=CC=C4N=C3N2C=C1)C5=CC=CC=C5Cl
The following data is based on the product molecular weight 397.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Kim DJ, Lee MH, Reddy K, Li Y, Lim DY, Xie H, Lee SY, Yeom YI, Bode AM, Dong Z. CInQ-03, a novel allosteric MEK inhibitor, suppresses cancer growth in vitro and in vivo. Carcinogenesis. 2013 Feb 14. [Epub ahead of print] PubMed PMID: 23354306.