WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406373

CAS#: 267645-83-0

Description: BMS-337197 is a a potent inhibitor of IMPDH with potential anticancer activity.

Chemical Structure

CAS# 267645-83-0

Theoretical Analysis

MedKoo Cat#: 406373
Name: BMS-337197
CAS#: 267645-83-0
Chemical Formula: C26H27N5O5
Exact Mass: 489.20122
Molecular Weight: 489.52
Elemental Analysis: C, 63.79; H, 5.56; N, 14.31; O, 16.34

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Synonym: BMS337197; BMS 337197; BMS-337197.

IUPAC/Chemical Name: N-(2-(2-((3-methoxy-4-(oxazol-5-yl)phenyl)amino)oxazol-5-yl)phenyl)-N-methyl-2-morpholinoacetamide


InChi Code: InChI=1S/C26H27N5O5/c1-30(25(32)16-31-9-11-34-12-10-31)21-6-4-3-5-19(21)24-15-28-26(36-24)29-18-7-8-20(22(13-18)33-2)23-14-27-17-35-23/h3-8,13-15,17H,9-12,16H2,1-2H3,(H,28,29)


Appearance: white solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 489.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Beevers RE, Buckley GM, Davies N, Fraser JL, Galvin FC, Hannah DR, Haughan AF, Jenkins K, Mack SR, Pitt WR, Ratcliffe AJ, Richard MD, Sabin V, Sharpe A, Williams SC. Low molecular weight indole fragments as IMPDH inhibitors. Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. Epub 2006 Feb 17. PubMed PMID: 16483769.

2: Dhar TG, Guo J, Shen Z, Pitts WJ, Gu HH, Chen BC, Zhao R, Bednarz MS, Iwanowicz EJ. A modified approach to 2-(N-aryl)-1,3-oxazoles: application to the synthesis of the IMPDH inhibitor BMS-337197 and analogues. Org Lett. 2002 Jun 13;4(12):2091-3. PubMed PMID: 12049525.


10.0mg / Not available

Additional Information