WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 401152

CAS#: 582315-72-8

Description: BMS-265246 is a potent CDK1/CDK2 selective inhibitor [(CDK1/cycB IC(50)=6 nM, CDK2/cycE IC(50)=9 nM)].

Chemical Structure

CAS# 582315-72-8

Theoretical Analysis

MedKoo Cat#: 401152
Name: BMS-265246
CAS#: 582315-72-8
Chemical Formula: C18H17F2N3O2
Exact Mass: 345.12888
Molecular Weight: 345.34
Elemental Analysis: C, 62.60; H, 4.96; F, 11.00; N, 12.17; O, 9.27

Price and Availability

Size Price Availability Quantity
25.0mg USD 250.0 Same day
50.0mg USD 450.0 Same day
100.0mg USD 750.0 Same day
200.0mg USD 1250.0 Same day
500.0mg USD 2150.0 Same day
1.0g USD 3250.0 Same day
2.0g USD 5650.0 2 Weeks
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Synonym: BMS265246; BMS-265246; BMS 265246.

IUPAC/Chemical Name: (4-butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(2,6-difluoro-4-methylphenyl)methanone


InChi Code: InChI=1S/C18H17F2N3O2/c1-3-4-5-25-17-11(8-21-18-12(17)9-22-23-18)16(24)15-13(19)6-10(2)7-14(15)20/h6-9H,3-5H2,1-2H3,(H,21,22,23)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >5 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 345.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1: Misra RN, Xiao Hy, Rawlins DB, Shan W, Kellar KA, Mulheron JG, Sack JS, Tokarski JS, Kimball SD, Webster KR. 1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: highly potent 2,6-Difluorophenacyl analogues. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2405-8. PubMed PMID: 12824044.

Additional Information