WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406216
Description: AHL196 is a FLT3 inhibitor.
MedKoo Cat#: 406216
Chemical Formula: C20H16F3N3O2
Exact Mass: 387.11946
Molecular Weight: 387.36
Elemental Analysis: C, 62.01; H, 4.16; F, 14.71; N, 10.85; O, 8.26
This product is not in stock, which may be available by custom synthesis.
For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge).
Quote less than 1g will not be provided. To request quote, please email to sales @medkoo.com or click below button.
Note: Price will be listed if it is available in the future.
Synonym: AHL-196; AHL196; AHL 196.
IUPAC/Chemical Name: 1-(4-((2-methylpyridin-4-yl)oxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
InChi Key: GISIPUFWENYLFB-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H16F3N3O2/c1-13-11-18(9-10-24-13)28-17-7-5-15(6-8-17)25-19(27)26-16-4-2-3-14(12-16)20(21,22)23/h2-12H,1H3,(H2,25,26,27)
SMILES Code: O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(OC3=CC(C)=NC=C3)C=C2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >5 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 387.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Weisberg E, Roesel J, Furet P, Bold G, Imbach P, FlÃ¶rsheimer A, Caravatti G, Jiang J, Manley P, Ray A, Griffin JD. Antileukemic Effects of Novel First- and Second-Generation FLT3 Inhibitors: Structure-Affinity Comparison. Genes Cancer. 2010 Oct;1(10):1021-32. doi: 10.1177/1947601910396505. PubMed PMID: 21779428; PubMed Central PMCID: PMC3092267.