WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 406216
Description: AHL196 is a FLT3 inhibitor.
MedKoo Cat#: 406216
Chemical Formula: C20H16F3N3O2
Exact Mass: 387.11946
Molecular Weight: 387.36
Elemental Analysis: C, 62.01; H, 4.16; F, 14.71; N, 10.85; O, 8.26
AHL196, purity > 98%, is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to firstname.lastname@example.org to inquire quote.
Synonym: AHL-196; AHL196; AHL 196.
IUPAC/Chemical Name: 1-(4-((2-methylpyridin-4-yl)oxy)phenyl)-3-(3-(trifluoromethyl)phenyl)urea
InChi Key: GISIPUFWENYLFB-UHFFFAOYSA-N
InChi Code: InChI=1S/C20H16F3N3O2/c1-13-11-18(9-10-24-13)28-17-7-5-15(6-8-17)25-19(27)26-16-4-2-3-14(12-16)20(21,22)23/h2-12H,1H3,(H2,25,26,27)
SMILES Code: O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(OC3=CC(C)=NC=C3)C=C2
The following data is based on the product molecular weight 387.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Weisberg E, Roesel J, Furet P, Bold G, Imbach P, FlÃ¶rsheimer A, Caravatti G, Jiang J, Manley P, Ray A, Griffin JD. Antileukemic Effects of Novel First- and Second-Generation FLT3 Inhibitors: Structure-Affinity Comparison. Genes Cancer. 2010 Oct;1(10):1021-32. doi: 10.1177/1947601910396505. PubMed PMID: 21779428; PubMed Central PMCID: PMC3092267.