WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 406312

CAS#: 750575-23-6

Description: AG-024104 is a broad spectrum cyclin-​dependent kinase inhibitors with potential anticancer activity.

Chemical Structure

CAS# 750575-23-6

Theoretical Analysis

MedKoo Cat#: 406312
Name: AG-024104
CAS#: 750575-23-6
Chemical Formula: C24H28F2N6O4S2
Exact Mass: 566.15815
Molecular Weight: 566.64
Elemental Analysis: C, 50.87; H, 4.98; F, 6.71; N, 14.83; O, 11.29; S, 11.32

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: AG024104; AG 024104; AG-024104

IUPAC/Chemical Name: (4-amino-2-((1-((6-(2-(dimethylamino)ethoxy)pyridin-3-yl)sulfonyl)piperidin-4-yl)amino)thiazol-5-yl)(2,6-difluorophenyl)methanone


InChi Code: InChI=1S/C24H28F2N6O4S2/c1-31(2)12-13-36-19-7-6-16(14-28-19)38(34,35)32-10-8-15(9-11-32)29-24-30-23(27)22(37-24)21(33)20-17(25)4-3-5-18(20)26/h3-7,14-15H,8-13,27H2,1-2H3,(H,29,30)


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs

Storage Condition: 0 – 4 oC for short term (weeks to 1 month) or -20 oC for long terms (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly.

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 566.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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1. Jessen, Bart A.; Lee, Leo; Koudriakova, Tatiana; Haines, Morgan; Lundgren, Karen; Price, Sharon; Nonomiya, Jim; Lewis, Cristina; Stevens, Gregory J. Peripheral white blood cell toxicity induced by broad spectrum cyclin-dependent kinase inhibitors. Journal of Applied Toxicology (2007), 27(2), 133-142

2. Chu, Shao Song; Alegria, Larry Andrew; Bleckman, Ted Michael; Chong, Wesley K. M.; Duvadie, Rohit K.; Li, Lin; Reich, Siegfried H.; Romines, William H.; Wallace, Michael B.; Yang, Yi. Preparation of thiazolylamino benzamide derivatives as modulators of cell proliferation and inhibitors of protein kinases. PCT Int. Appl. (2003), WO 2003004467 A2 20030116.

Additional Information