WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 206009

CAS#: 1095806-02-2 (free acid)

Description: TriN2755 is a synthetic triazene derivative with antineoplastic activity. Upon metabolic activation via N-demethylation, TriN2755 is converted into highly reactive carbocations that can alkylate DNA and other macromolecules, thereby resulting in DNA cross links, inhibiting DNA replication and repair, and subsequently inducing apoptosis. This agent has high hydrophilicity and photostability and shows a favorable toxicity profile over the other triazenes.

Chemical Structure

CAS# 1095806-02-2 (free acid)

Theoretical Analysis

MedKoo Cat#: 206009
Name: TriN2755
CAS#: 1095806-02-2 (free acid)
Chemical Formula: C20H22N4O5
Exact Mass: 398.159
Molecular Weight: 398.419
Elemental Analysis: C, 60.29; H, 5.57; N, 14.06; O, 20.08

Price and Availability

This product is not in stock, which may be available by custom synthesis. For cost-effective reason, minimum order is 1g (price is usually high, lead time is 2~3 months, depending on the technical challenge). Quote less than 1g will not be provided. To request quote, please email to sales or click below button.
Note: Price will be listed if it is available in the future.

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Synonym: TriN2755; TriN-2755; Tri N2755.

IUPAC/Chemical Name: (E)-(3-(4-(4-(3,3-dimethyltriaz-1-en-1-yl)benzoyl)phenoxy)propanoyl)glycine


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >5 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 398.419 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

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Reconstitution Calculator

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 1: Athanasiadi I, Geigy C, Hilger RA, Meier V, Rohrer Bley C. Safety,
tolerability and pharmacokinetic properties of the novel triazene TriN 2755 in
tumour bearing dogs - a phase I study(†). Vet Comp Oncol. 2015 Feb 16. doi:
10.1111/vco.12145. [Epub ahead of print] PubMed PMID: 25689225.

Additional Information

  Related CAS#
1095806-02-2 (TriN2755 free acid)
1095806-18-0 (TriN2755 sodium salt)