WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 206038
CAS#: 70-00-8
Description: Trifluridine (also called trifluorothymidine or TFT) is an anti-herpesvirus antiviral drug, used primarily on the eye. It was sold under the trade name, Viroptic, by Glaxo Wellcome, now merged into GlaxoSmithKline. The brand is now owned by Monarch Pharmaceuticals, which is wholly owned by King Pharmaceuticals. It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the -CF3 group added to the uracil component blocks base pairing. It is a component of the experimental anti-cancer drug TAS-102.
MedKoo Cat#: 206038
Name: Trifluridine
CAS#: 70-00-8
Chemical Formula: C10H11F3N2O5
Exact Mass: 296.06201
Molecular Weight: 296.2
Elemental Analysis: C, 40.55; H, 3.74; F, 19.24; N, 9.46; O, 27.01
Trifluridine, purity > 98%, is in stock. The same day shipping out after order is received.
Synonym: FTD ; NSC 529182; NSC-529182; NSC529182; NSC 75520; NSC-75520; NSC75520; Trifluorothymidine; Viroptic; 2-Deoxy-5-trifluoromethyluridine; Trifluridine; 5-Trifluorothymidine;
IUPAC/Chemical Name: 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(trifluoromethyl)pyrimidine-2,4(1H,3H)-dione.
InChi Key: VSQQQLOSPVPRAZ-RRKCRQDMSA-N
InChi Code: InChI=1S/C10H11F3N2O5/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2,5-7,16-17H,1,3H2,(H,14,18,19)/t5-,6+,7+/m0/s1
SMILES Code: O=C1NC(C(C(F)(F)F)=CN1[C@@H]2O[C@H](CO)[C@@H](O)C2)=O
The following data is based on the product molecular weight 296.2 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
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