WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 206078

CAS#: 59653-73-5

Description: Teroxirone, also known as Triglycidyl Isocyanurate and Tris(2,3-epoxypropyl) Isocyanurate, is a triazene triepoxide with antineoplastic activity. Teroxine alkylates and cross-links DNA, thereby inhibiting DNA replication.

Chemical Structure

CAS# 59653-73-5

Theoretical Analysis

MedKoo Cat#: 206078
Name: Teroxirone
CAS#: 59653-73-5
Chemical Formula: C12H15N3O6
Exact Mass: 297.09609
Molecular Weight: 297.26
Elemental Analysis: C, 48.48; H, 5.09; N, 14.14; O, 32.29

Size Price Shipping out time Quantity
1g USD 80 2 Weeks
5g USD 190 2 Weeks
10g USD 250 2 Weeks
50g USD 450 2 Weeks
100g USD 650 2 Weeks
Inquire bulk and customized quantity

Pricing updated 2021-03-02. Prices are subject to change without notice.

Teroxirone, purity > 98%, is in stock. Current shipping out time is about 2 weeks after order is received. CoA, QC data and MSDS documents are available in one week after order is received. Delivery time: overnight (USA/Canada); 3-5 days (worldwide). Shipping fee: from $30.00 (USA); from $45.00 (Canada); from $70.00 (international).

Synonym: Teroxirone; Henkels Compound; alphaTGI; alpha-triglycidyl isocyanurate; Triglycidyl Isocyanurate; Tris(2,3-epoxypropyl) Isocyanurate.

IUPAC/Chemical Name: 1,3,5-tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione


Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>5 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Handling Instructions:

Preparing Stock Solutions

The following data is based on the product molecular weight 297.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

1: Wang JP, Lin KH, Liu CY, Yu YC, Wu PT, Chiu CC, Su CL, Chen KM, Fang K. Teroxirone inhibited growth of human non-small cell lung cancer cells by activating p53. Toxicol Appl Pharmacol. 2013 Aug 15;273(1):110-120. doi: 10.1016/j.taap.2013.08.007. [Epub ahead of print] PubMed PMID: 23954467.

2: Rubin J, Kovach JS, Ames MM, Moertel CG, Creagan ET, O'Connell MJ. Phase I study of two schedules of teroxirone. Cancer Treat Rep. 1987 May;71(5):489-92. PubMed PMID: 3567975.

3: Ames MM, Kovach JS, Rubin J. Pharmacological characterization of teroxirone, a triepoxide antitumor agent, in rats, rabbits, and humans. Cancer Res. 1984 Sep;44(9):4151-6. PubMed PMID: 6744326.

4: Neidhart JA, Derocher D, Grever MR, Kraut EH, Malspeis L. Phase I trial of teroxirone. Cancer Treat Rep. 1984 Sep;68(9):1115-9. PubMed PMID: 6478450

Additional Information

 Related CAS#