WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 205996
Description: T900607 is a pentafluorophenylsulfonamide compound with potential antineoplastic activity. T900607 inhibits tubulin polymerization by binding irreversibly to colchicine binding sites, resulting in cell cycle arrest and apoptosis.
MedKoo Cat#: 205996
Chemical Formula: C14H10F5N3O4S
Exact Mass: 411.03122
Molecular Weight: 411.3
Elemental Analysis: C, 40.88; H, 2.45; F, 23.10; N, 10.22; O, 15.56; S, 7.80
T900607 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to email@example.com to inquire quote.
Synonym: T900607, T-900607, T 900607, T607; T-607, T 607
IUPAC/Chemical Name: N-(4-Methoxy-3-ureidophenyl)-2,3,4,5,6-pentafluorobenzenesulfonamide
InChi Key: FSXLOWIFSZNIMV-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H10F5N3O4S/c1-26-7-3-2-5(4-6(7)21-14(20)23)22-27(24,25)13-11(18)9(16)8(15)10(17)12(13)19/h2-4,22H,1H3,(H3,20,21,23)
SMILES Code: O=S(C1=C(F)C(F)=C(F)C(F)=C1F)(NC2=CC=C(OC)C(NC(N)=O)=C2)=O
The following data is based on the product molecular weight 411.3 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|
1: Gelmon KA, Belanger K, Soulieres D, Britten C, Chia S, Charpentier D, Chi K, Powers J, Walsh W, Seymour L. A phase I study of T900607 given once every 3 weeks in patients with advanced refractory cancers; National Cancer Institute of Canada Clinical Trials Group (NCIC-CTG) IND 130. Invest New Drugs. 2005 Oct;23(5):445-53. PubMed PMID: 16133796.