Molidustat
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    WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 525715

CAS#: 1154028-82-6

Description: Molidustat, also known as BAY 85-3934, is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells. Phase I data have shown that inhibition of HIF-PH by Molidustat results in an increase in endogenous production of EPO. Molidustat is currently clinical trials at Bayer for the treatment of patients suffering from renal anemia due to chronic kidney disease.


Chemical Structure

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Molidustat
CAS# 1154028-82-6

Theoretical Analysis

MedKoo Cat#: 525715
Name: Molidustat
CAS#: 1154028-82-6
Chemical Formula: C13H14N8O2
Exact Mass: 314.12397
Molecular Weight: 314.3
Elemental Analysis: C, 49.68; H, 4.49; N, 35.65; O, 10.18

Size Price Shipping out time Quantity
25mg USD 150 Same Day
50mg USD 250 Same Day
100mg USD 450 Same Day
200mg USD 650 Same Day
500mg USD 1250 Same Day
1g USD 2150 Same Day
2g USD 3650 Same Day
5g USD 5450 Same Day
Inquire bulk and customized quantity

Pricing updated 2021-03-07. Prices are subject to change without notice.

Molidustat (BAY 85-3934 ), purity > 98%, is in stock.The same day shipping out after order is received.

Related CAS #: 1154025-82-6    

Synonym: BAY 85-3934; BAY-85-3934; BAY85-3934; BAY 853934; BAY-853934; BAY853934; Molidustat.

IUPAC/Chemical Name: 2-(6-morpholinopyrimidin-4-yl)-4-(1H-1,2,3-triazol-1-yl)-1H-pyrazol-3(2H)-one

InChi Key: IJMBOKOTALXLKS-UHFFFAOYSA-N

InChi Code: InChI=1S/C13H14N8O2/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2,7-9,17H,3-6H2

SMILES Code: O=C1N(C2=NC=NC(N3CCOCC3)=C2)NC=C1N4N=NC=C4

Appearance:
Solid powder

Purity:
>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:
Soluble in DMSO, DMF, and 1:1 DMF:PBS

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:
2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 314.3 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

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Additional Information