WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 206214
Description: LY3023414 is a small molecule that has been shown in vitro to be a selective ATP-competitive inhibitor of PI3Kα and mTOR, DNA-PK, and other class I PI3K family members. In vitro, LY3023414 has demonstrated inhibitory activity against PI3K and mTOR in tumor cells, as well as antiproliferative activity and cell cycle effects. In addition, in vitro, LY3023414 inhibits the ability of PI3K and mTOR to phosphorylate substrates in the PI3K/mTOR pathway. LY3023414 is being investigated in a phase I clinical trial.
MedKoo Cat#: 206214
Chemical Formula: C23H26N4O3
Exact Mass: 406.2005
Molecular Weight: 406.486
Elemental Analysis: C, 67.96; H, 6.45; N, 13.78; O, 11.81
Synonym: LY3023414; LY-3023414; LY 3023414.
IUPAC/Chemical Name: (S)-8-(5-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-(2-methoxypropyl)-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one
InChi Key: ACCFLVVUVBJNGT-AWEZNQCLSA-N
InChi Code: InChI=1S/C23H26N4O3/c1-14(30-5)13-27-21-18-9-15(16-8-17(11-24-10-16)23(2,3)29)6-7-19(18)25-12-20(21)26(4)22(27)28/h6-12,14,29H,13H2,1-5H3/t14-/m0/s1
SMILES Code: O=C(N1C[C@@H](OC)C)N(C)C2=C1C3=CC(C4=CC(C(C)(O)C)=CN=C4)=CC=C3N=C2