WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 205975
Description: Lerisetron is a serotonin type 3 (5-HT3) receptor antagonist with antiemetic activity. Lerisetron specifically binds to 5-HT3 receptors, located peripherally on vagus nerve terminals and centrally in the chemoreceptor trigger zone (CTZ) of the area postrema, which may result in suppression of chemotherapy-induced nausea and vomiting. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
MedKoo Cat#: 205975
Chemical Formula: C18H20N4
Exact Mass: 292.1688
Molecular Weight: 292.3782
Elemental Analysis: C, 73.94; H, 6.89; N, 19.16
Lerisetron is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to email@example.com to inquire quote.
Synonym: Lerisetron; F0930RS.
IUPAC/Chemical Name: 1-benzyl-2-(piperazin-1-yl)-1H-benzo[d]imidazole
InChi Key: PWWDCRQZITYKDV-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H20N4/c1-2-6-15(7-3-1)14-22-17-9-5-4-8-16(17)20-18(22)21-12-10-19-11-13-21/h1-9,19H,10-14H2
SMILES Code: C1(N2CCNCC2)=NC3=CC=CC=C3N1CC4=CC=CC=C4
The following data is based on the product molecular weight 292.3782 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|