WARNING: This product is for research use only, not for human or veterinary use.
GRD081 is a dual PI3K/mTOR inhibitor. The no-observed-adverse-effect level (NOAEL) of GRD081 was 1mg/kg/day for beagle dogs and less than 2mg/kg/day for SD rats.
Price and Availability
GRD081 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to firstname.lastname@example.org to inquire quote.
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MedKoo Cat#: 206085
GRD081; GRD-081; GRD 081.
>98% (or refer to the Certificate of Analysis)
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Soluble in DMSO, not in water
>2 years if stored properly
This drug may be formulated in DMSO
Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Harmonized System Code:
1: Xia Z, Gao T, Zong Y, Zhang X, Mao Y, Yuan B, Lu G. Evaluation of subchronic toxicity of GRD081, a dual PI3K/mTOR inhibitor, after 28-day repeated oral administration in Sprague-Dawley rats and beagle dogs. Food Chem Toxicol. 2013 Oct 15;62C:687-698. doi: 10.1016/j.fct.2013.10.001. [Epub ahead of print] PubMed PMID: 24140470.