WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 556340
CAS#: 2598164-15-7
Description: TRV-7019 is a BBB-penetrable radioligand for brain imaging that target butyrylcholinesterase. TRV-7019 can be used for the diagnosis of an amyloid disease, multiple sclerosis, a brain tumor, or butyrylcholinesterase activity.
MedKoo Cat#: 556340
Name: TRV-7019
CAS#: 2598164-15-7
Chemical Formula: C14H12INO3
Exact Mass: 368.9862
Molecular Weight: 369.1585
Elemental Analysis: C, 45.55; H, 3.28; I, 34.38; N, 3.79; O, 13.00
Synonym: TRV-7019; TRV 7019; TRV7019;
IUPAC/Chemical Name: 4-iodobenzyl 6-methoxypicolinate
InChi Key: AVKHPDWARYICID-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H12INO3/c1-18-13-4-2-3-12(16-13)14(17)19-9-10-5-7-11(15)8-6-10/h2-8H,9H2,1H3
SMILES Code: O=C(C1=NC(OC)=CC=C1)OCC2=CC=C(I)C=C2
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 369.1585 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
Sultan Darvesh, et al. Butyrylcholinesterase compounds and use in diseases of the nervous system. Patent WO2021026429A1.
