WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 556333
CAS#: 2143896-83-5 (HCl)
Description: PKUMDL-LC-101-D04 is an allosteric activator of glutathione peroxidase 4 (GPX4).
MedKoo Cat#: 556333
Name: PKUMDL-LC-101-D04
CAS#: 2143896-83-5 (HCl)
Chemical Formula: C14H23ClN4O2S2
Exact Mass:
Molecular Weight: 378.93
Elemental Analysis: C, 44.38; H, 6.12; Cl, 9.36; N, 14.79; O, 8.44; S, 16.92
Related CAS #: 2143896-83-5 (HCl) 2143896-82-4 (free base)
Synonym: PKUMDL-LC-101-D04 ;
IUPAC/Chemical Name: N-(2-aminoethyl)-4-[[(cyclopentylamino)thioxomethyl]amino]-benzenesulfonamide, monohydrochloride
InChi Key: FELDRJSFLBINQS-UHFFFAOYSA-N
InChi Code: InChI=1S/C14H22N4O2S2.ClH/c15-9-10-16-22(19,20)13-7-5-12(6-8-13)18-14(21)17-11-3-1-2-4-11;/h5-8,11,16H,1-4,9-10,15H2,(H2,17,18,21);1H
SMILES Code: O=S(C1=CC=C(NC(NC2CCCC2)=S)C=C1)(NCCN)=O.[H]Cl
Appearance: To be determined
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: To be determined
Shelf Life: >2 years if stored properly
Drug Formulation: To be determined
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
The following data is based on the product molecular weight 378.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
1. Li, C., Deng, X., Zhang, W., et al. Novel allosteric activators for ferroptosis regulator glutathione peroxidase 4. J. Med. Chem. 62(1), 266-275 (2019).
