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MedKoo CAT#: 206145

CAS#: 1383370-92-0

Description: DTP348 is an oral dual CAIX inhibitor/ radiosensitizer. DTP 348 is an oral dual drug with two mechanisms of action: (1). carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2). radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety.

Price and Availability

Size Price Shipping out time Quantity
Inquire bulk and customized quantity

Pricing updated 2020-07-12. Prices are subject to change without notice.

DTP348 is not in stock, but may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Chemical Structure


Theoretical Analysis

MedKoo Cat#: 206145
Name: DTP348
CAS#: 1383370-92-0
Chemical Formula: C6H11N5O4S
Exact Mass: 249.05317
Molecular Weight: 249.25
Elemental Analysis: C, 28.91; H, 4.45; N, 28.10; O, 25.68; S, 12.86

Synonym: DTP348; DTP 348; DTP-348.

IUPAC/Chemical Name: 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylsulfamide.


InChi Code: InChI=1S/C6H11N5O4S/c1-5-8-4-6(11(12)13)10(5)3-2-9-16(7,14)15/h4,9H,2-3H2,1H3,(H2,7,14,15)

SMILES Code: O=S(NCCN1C([N+]([O-])=O)=CN=C1C)(N)=O

Technical Data

Solid powder

>98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Soluble in DMSO, not in water

Shelf Life:
>2 years if stored properly

Drug Formulation:
This drug may be formulated in DMSO

Stock Solution Storage:
0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:

Additional Information



1. Rami, Marouan; Dubois, Ludwig; Parvathaneni, Nanda-Kumar; Alterio, Vincenzo; van Kuijk, Simon J. A.; Monti, Simona Maria; Lambin, Philippe; De Simone, Giuseppina; Supuran, Claudiu T.; Winum, Jean-Yves. Hypoxia-​Targeting Carbonic Anhydrase IX Inhibitors by a New Series of Nitroimidazole-​Sulfonamides​/Sulfamides​/Sulfamates. Journal of Medicinal Chemistry (2013), 56(21), 8512-8520. |