WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 556223

CAS#: 2387524-59-4

Description: SUN24595, also known as NF-κΒ activator 1, is a potent NF-κΒ activator with an EC50 of 0.9 μM. SUN24595 induces superoxide dismutase (SOD)2 mRNA expression. SUN24595 was first reported in European Journal of Medicinal Chemistry (2021), 210, 112952. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page:

Chemical Structure

CAS# 2387524-59-4

Theoretical Analysis

MedKoo Cat#: 556223
Name: SUN24595
CAS#: 2387524-59-4
Chemical Formula: C16H11FN2O2S
Exact Mass: 314.05
Molecular Weight: 314.334
Elemental Analysis: C, 61.14; H, 3.53; F, 6.04; N, 8.91; O, 10.18; S, 10.20

Price and Availability

Size Price Availability Quantity
50mg USD 550 2 Weeks
100mg USD 950 2 Weeks
200mg USD 1650 2 Weeks
500mg USD 2650 2 Weeks
1g USD 4250 2 Weeks
2g USD 6450 2 Weeks
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Synonym: NF-κΒ activator 1; SUN24595; SUN-24595; SUN 24595;

IUPAC/Chemical Name: 3-(2-((2-fluorophenyl)amino)thiazol-4-yl)benzoic acid


InChi Code: InChI=1S/C16H11FN2O2S/c17-12-6-1-2-7-13(12)18-16-19-14(9-22-16)10-4-3-5-11(8-10)15(20)21/h1-9H,(H,18,19)(H,20,21)


Appearance: To be determined

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

More Info:

Biological target:
In vitro activity:
In vivo activity:

Preparing Stock Solutions

The following data is based on the product molecular weight 314.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
In vitro protocol:
In vivo protocol:

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Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-ҡB activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952 [Content Brief]