WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 205959
Description: Cytochlor is a radio-sensitizing pyrimidine nucleoside with potential antineoplastic activity. Cytochlor is metabolized first to a phosphate derivative, CldCMP, by the enzyme deoxycytidine kinase and then to the active uracyl derivative, CldUMP, by the enzyme dCMP deaminase; deoxycytidine kinase and dCMP deaminase have been found in abnormally high concentrations in most cancers. CldUMP, the active metabolite, incorporates into DNA and, upon exposure to radiation, induces the formation of uracil radicals and double-strand DNA breaks.
MedKoo Cat#: 205959
Chemical Formula: C9H12ClN3O4
Exact Mass: 261.05163
Molecular Weight: 261.66
Elemental Analysis: C, 41.31; H, 4.62; Cl, 13.55; N, 16.06; O, 24.46
Cytochlor, purity > 98%, is not in stock, may be available through custom synthesis. Minimum 1 gram order is requested. Current shipping out time is about 70 days after order is received.
Synonym: CIdC. Cytochlor; Cytidine 5-chloro-2-deoxy.
IUPAC/Chemical Name: 4-amino-5-chloro-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
InChi Key: NGGRGTWYSXYVDK-RRKCRQDMSA-N
InChi Code: InChI=1S/C9H12ClN3O4/c10-4-2-13(9(16)12-8(4)11)7-1-5(15)6(3-14)17-7/h2,5-7,14-15H,1,3H2,(H2,11,12,16)/t5-,6+,7+/m0/s1
SMILES Code: O=C1N=C(N)C(Cl)=CN1[C@@H]2O[C@H](CO)[C@@H](O)C2
The following data is based on the product molecular weight 261.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|1 mM||1.15 mL||5.76 mL||11.51 mL|
|5 mM||0.23 mL||1.15 mL||2.3 mL|
|10 mM||0.12 mL||0.58 mL||1.15 mL|
|50 mM||0.02 mL||0.12 mL||0.23 mL|