WARNING: This product is for research use only, not for human or veterinary use.

MedKoo CAT#: 205612

CAS#: 213406-50-9

Description: RG7304, also known as R7304 or CK-127, is a MEK inhibitor currently in clinical trials.

Chemical Structure

CAS# 213406-50-9

Theoretical Analysis

MedKoo Cat#: 205612
Name: RG7304
CAS#: 213406-50-9
Chemical Formula: C12H12N4O
Exact Mass: 228.1011
Molecular Weight: 228.255
Elemental Analysis: C, 63.15; H, 5.30; N, 24.55; O, 7.01

Price and Availability

Size Price Availability Quantity
Bulk inquiry

Synonym: CKI27; CK127; CK 127; RG7304; RG7304; RG 7304 R7304.

IUPAC/Chemical Name: (E)-5-(2-benzylidene-1-methylhydrazinyl)pyridazin-3(2H)-one


InChi Code: InChI=1S/C12H12N4O/c1-16(11-7-12(17)15-13-9-11)14-8-10-5-3-2-4-6-10/h2-9H,1H3,(H,15,17)/b14-8+


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Preparing Stock Solutions

The following data is based on the product molecular weight 228.255 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Dilution Calculator

Calculate the dilution required to prepare a stock solution.

 1: Chiou GC, Xuan B, Yamasaki T, Okawara T. Anti-inflammation and
antifibroblastic actions of interleukin-1 blockers. J Ocul Pharmacol Ther. 1998
Aug;14(4):375-88. PubMed PMID: 9715441.

Additional Information

CKI 27 (RG7304) is a MEK inhibitor currently in clinical trials.