WARNING: This product is for research use only, not for human or veterinary use.
MedKoo CAT#: 205814
Description: APC-300 is a natural compound that, in pre-clinical studies, has been shown to not only inhibit the growth, but also stimulates the death of human prostate cancer cells. APC-300 is a small molecule signal transduction inhibitor that acts as an anti-inflammatory agent and blocks prostate cancer progression in in vivo models of the disease. In addition to prostate cancer, APC-300 has also demonstrated efficacy in disease models of human melanoma and pancreatic cancer. Adamis believes that APC-300 may have potential applications in the treatment of several tumor types. APC-300 is currently in preclinical development.
MedKoo Cat#: 205814
Synonym: APC300; APC-300; APC 300
IUPAC/Chemical Name: NONE
1: Manner H, Enderle MD, Pech O, May A, Plum N, Riemann JF, Ell C, Eickhoff A. Second-generation argon plasma coagulation: two-center experience with 600 patients. J Gastroenterol Hepatol. 2008 Jun;23(6):872-8. doi: 10.1111/j.1440-1746.2008.05437.x. PubMed PMID: 18565020.
2: Manner H, May A, Faerber M, Pech O, Plum N, Ell C. The tissue effect of second generation argon plasma coagulation (VIO APC) in comparison to standard APC and Nd:YAG laser in vitro. Acta Gastroenterol Belg. 2007 Oct-Dec;70(4):352-6. PubMed PMID: 18330091.
3: Dang BW, Zhang J. [The efficacy of endobronchial argon plasma coagulation in the management of intraluminal obstructive lesions of the central airway]. Zhonghua Jie He He Hu Xi Za Zhi. 2007 May;30(5):330-3. Chinese. PubMed PMID: 17651635.
4: Nomura T, Miyashita M, Makino H, Maruyama H, Katsuta M, Kashiwabara M, Takahashi K, Sasajima K, Yamashita K, Tajiri T. Argon plasma coagulation for the treatment of superficial esophageal carcinoma. J Nippon Med Sch. 2007 Apr;74(2):163-7. PubMed PMID: 17507793.
5: Miyazawa T, Nawashiro H, Shima K, Bertalanffy H. Early experiences of haemostasis on brain tumour surgery with Argon Plasma Coagulation (APC). Acta Neurochir (Wien). 2000;142(11):1247-51. PubMed PMID: 11201639.
6: Roach SK, Kozarek RA, Raltz SL, Sumida SE. In vitro evaluation of integrity and sterilization of single-use argon beam plasma coagulation probes. Am J Gastroenterol. 1999 Jan;94(1):139-43. PubMed PMID: 9934744.
7: Katsuura Y, Aoki K, Tanabe H, Kiyoki M, Funatsu A. Characteristic effects of activated human protein C on tissue thromboplastin-induced disseminated intravascular coagulation in rabbits. Thromb Res. 1994 Nov 15;76(4):353-62. PubMed PMID: 7871494.